SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Demand creation for HIV testing services: A systematic review and meta-analysis

2023

Background HIV testing services (HTS) are the first steps in reaching the UNAIDS 95-95-95 goals to achieve and maintain low HIV incidence. Evaluating the effectiveness of different demand creation interventions...

Methodologies used in studies examining substance abuse, violence and HIV/AIDS (SAVA) constructs using a syndemic framework: A scoping review

2023

The syndemic theoretical framework has been used in health disparities research to explain several co-occurring epidemics, particularly in populations facing disparate health conditions. A prominent example of this is seen...

Global overview of suicidal behavior and associated risk factors among people living with human immunodeficiency virus: A scoping review

2023

Death by suicide is a major public health problem. People living with human immunodeficiency virus (PLHIV) have higher risk of suicidal behavior than the general population. The aim of this...

Barriers and facilitators to maintaining a high level of polypharmacy adherence in people living with HIV: A scoping review

2023

Objectives: With the prolongation of life span and increasing incidence of comorbidities, polypharmacy has become a challenge for people living with HIV/AIDS (PLWH). This review aimed to identify barriers and...

Does telehealth affect the adherence to ART among patients with HIV? A systematic review and meta-analysis

2023

Background Several studies have shown different effects of telehealth interventions on adherence to Antiretroviral therapy (ART) among people living with HIV. This study conducted a meta-analysis of Randomized Controlled Trials...

HIV-1 Tat amino acid residues that influence Tat-TAR binding affinity: A scoping review

2023

HIV-1 remains a global health concern and to date, nearly 38 million people are living with HIV. The complexity of HIV-1 pathogenesis and its subsequent prevalence is influenced by several...

Monkeypox epidemiology, clinical presentation, and transmission: A systematic review

2023

BACKGROUND: The new zoonotic viral infection, monkeypox, is a global health issue. Our study aimed at studying the epidemiology, clinical presentation, complications, case fatality rate, and transmission among the present...

Immediate treatment for recent hepatitis C infection in people with high-risk behaviors: A systematic review and meta-analysis

2023

BACKGROUND AND AIMS: Direct-acting antivirals (DAAs) are almost exclusively approved for the treatment of chronic HCV. This poses a significant barrier to the treatment of recently acquired HCV because of...

A systematic review of sarcopenia prevalence and associated factors in people living with human immunodeficiency virus

2023

People living with human immunodeficiency virus (HIV) (PLWH) appear to be at an increased risk of sarcopenia, which can have a devastating effect on their life due to consequences such...

Strategies to increase couples HIV testing and counselling in sub-Saharan Africa: A systematic review

2023

INTRODUCTION: Couple HIV testing and counselling (CHTC) is associated with measurable benefits for HIV prevention and treatment. However, the uptake remains limited in much of sub-Saharan Africa, despite an expanded...

Association of hospitalization rate, mortality, and CD4 T cell count with comorbidity of COVID-19 and HIV: A systematic review and meta-analysis

2023

Epidemiological data demonstrate the greater severity of SARS-CoV-2 infection in HIV patients along with the more hospitalization, and mortality rates. Thus, this meta-analysis aimed to assess the possible differences in...

Uncovering the NAFLD burden in people living with HIV from high- and middle-income nations: A meta-analysis with a data gap from Subsaharan Africa

2023

INTRODUCTION: Non-alcoholic fatty liver disease (NAFLD) has become a significant concern among people living with HIV (PLHIV), albeit its burden remains unclear. The primary objective of this systematic review (SR)...

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