SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Factors associated with severity of pulmonary tuberculosis in people living with and without HIV: A systematic review

2026

Introduction Tuberculosis is a leading infectious cause of death and morbidity in people with and without HIV. Better identification of severe forms could help target early interventions to reduce mortality...

Vulnerability and non-adherence to treatment in cisgender women living with HIV/AIDS: A scoping review (2000–2024)

2026

Background Cisgender women are disproportionately affected by HIV/AIDS due to structural gender inequalities and intersecting social determinants, which generate vulnerability contexts that act as barriers to treatment adherence. Methods A...

Strategies to integrate non-communicable disease interventions in HIV and tuberculosis care contexts in low- and middle-income countries: A scoping review

2026

INTRODUCTION: Integration of management of tuberculosis (TB) and HIV with prevention and treatment of non-communicable diseases (NCDs) is a global priority. However, delivering the full spectrum of HIV/TB and NCD...

Syndemics and clinical impact of HIV and mental health conditions among people living with HIV: A systematic review and meta-analysis

2026

INTRODUCTION: People living with HIV (PLWH) may be exposed to harmful political, social, economic and environmental factors that exacerbate their risk of mental health conditions. Such factors can interact synergistically...

Broadly neutralizing antibodies for HIV therapy in clinical trials: A systematic review

2026

Background: Lifelong daily antiretroviral therapy (ART) effectively suppresses human immunodeficiency virus type 1 (HIV-1) replication but does not eradicate the virus, underscoring the urgent need for long-acting antivirals and functional cure...

The role of subtyping methodologies in HIV surveillance and vaccine development: A systematic review and meta-analysis

2026

BACKGROUND: HIV genetic diversity has increased over time, with recombinant forms becoming more prevalent and complicating subtype classification and surveillance, particularly in low-and-middle income countries (LMICs). Accurate subtyping is critical...

Interventions to improve access to sexual and reproductive health services for adolescents living with HIV in sub-Saharan Africa: A scoping review

2026

OBJECTIVE: Adolescents living with HIV (ALHIV) face barriers to accessing sexual and reproductive health (SRH) services, negatively affecting their health and quality of life. These challenges are particularly pronounced in...

Prevalence and risk factors for oropharyngeal, esophageal, and oral candidiasis in HIV-positive individuals: A systematic review and meta-analysis

2026

Background: Oral, oropharyngeal, and esophageal candidiasis are common forms of mucosal candidiasis (MC) in people living with human immunodeficiency virus/acquired immunodeficiency syndrome (PLWHA). Despite differences in infection sites, oral, oropharyngeal, and...

Obstetric nurses’ approach to evidence-based practice in breastfeeding within the context of HIV: A scoping review

2026

BACKGROUND/OBJECTIVES: Human immunodeficiency virus remains a significant public health challenge, with breastfeeding contributing to the risk of mother-to-child transmission. Although antiretroviral therapy significantly reduces this risk, obstetric nurses face complex...

Evaluating the effectiveness of digital health interventions for HIV prevention and treatment adherence among transgender populations: A systematic review and meta-analysis

2026

Background Transgender individuals face a disproportionate burden of HIV due to systemic barriers including stigma, discrimination, and limited access to gender-affirming healthcare. Digital health interventions (DHIs), such as mobile applications,...

Lived experiences of cancer care for people living with HIV who are treated for anal cancer: A scoping review

2026

OBJECTIVE: This scoping review aims to identify existing evidence on the lived experiences of people living with HIV and treated for anal cancer, and to identify what aspects of health...

Barriers and facilitators to healthcare access among Sub-Saharan African migrants in Europe: A scoping review

2026

Background Sub-Saharan African (SSA) migrants represent a significant and growing proportion of Europe’s diverse migrant population; yet face substantial barriers in accessing healthcare services. Understanding these barriers is essential for...

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