SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Risk factors for COVID-19 mortality among people living with HIV: A scoping review

2022

People living with HIV (PLWH) are particularly vulnerable to worsened outcomes of COVID-19. Therefore, the purpose of this work was to provide a scoping review of the literature to assess...

Impact of HIV-associated cognitive impairment on functional independence, frailty and quality of life in the modern era: A meta-analysis

2022

HIV-associated neurocognitive disorder (HAND) is an important sequela of HIV infection. Combined antiretroviral therapy (cART) has improved the health outcomes of many people living with HIV but has given rise...

Impact of supervised aerobic exercise on clinical physiological and mental parameters of people living with HIV: A systematic review and meta-analyses of randomized controlled trials

2022

Background: The benefits derived from supervised aerobic exercise in people living with human immunofeficiency virus- HIV (PLWH) have not yet been clearly identified.Objective: To evaluate the impact of supervised aerobic exercise on...

Meta-synthesis and science mapping analysis of HIV/HPV co-infection: A global perspective with emphasis on Africa

2022

BACKGROUND: Viral infections are emerging with diverse clinical relevance both in endemic environments and non-endemic regions of the world. Some of the viruses cause co-infections that are of public health...

Best practices to increase the uptake of HIV and HCV testing among people who use drugs

2022

Interventions that provide HIV and/or HCV testing have been offered in a variety of settings. These include community settings such as outpatient drug treatment clinics, mobile clinics, harm reduction services...

Understanding the epidemiological HIV risk factors and underlying risk context for youth residing in or originating from the Middle East and North Africa (MENA) region: A scoping review of the literature

2022

INTRODUCTION: HIV is the second leading cause of death among young people globally, and adolescents are the only group where HIV mortality is not declining. Middle East and North Africa...

Interventions to increase early infant diagnosis of HIV infection: A systematic review and meta-analysis

2022

OBJECTIVES: Early infant diagnosis (EID) of HIV infection increases antiretroviral therapy initiation, which reduces pediatric HIV-related morbidity and mortality. This review aims to critically appraise the effects of interventions to...

HIV/AIDS post-exposure prophylaxis knowledge and uptake among health professionals in Africa: Systematic review and meta-analysis

2022

Background: Healthcare workers in developing countries are at particularly increased risk of infections from blood-borne pathogens because of the high prevalence of such pathogens in their communities as well as the...

Comparative efficacy and safety of antifungal agents in the prophylaxis of oropharyngeal candidiasis among HIV-infected adults: A systematic review and network meta-analysis

2022

The objective of the study was to compare the efficacy and safety of antifungal agents used in the prevention of oropharyngeal candidiasis among HIV-infected adults. A systematic search was conducted...

Epigenome-wide epidemiologic studies of human immunodeficiency virus infection, treatment, and disease progression

2022

Despite significant advances in the treatment and care of people with HIV (PWH), several challenges remain in our understanding of disease pathogenesis to improve patient care. HIV infection can modify...

Effects of interleukin-10 -1082G/A and -592C/A gene polymorphisms on the risk of human immunodeficiency virus-1 infection: An updated meta-analysis

2022

This paper has aimed to review the available evidence on the association between Interleukin (IL) -10 -1082G/A, -592C/A gene polymorphisms and the risk of human immunodeficiency virus-1(HIV-1) infection. The data...

Queering poppers literature: A critical interpretive synthesis of health sciences research on alkyl nitrite use and Canadian policy

2022

BACKGROUND: Poppers (alkyl nitrites) are vasodilators used by many gay, bisexual, and other men who have sex with men (GBMSM) to relieve pain, enhance pleasure, and facilitate penetration during sex....

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