In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).
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Background People living with HIV (PLWH) face a significantly elevated risk of cardiovascular diseases (CVDs). This study aims to quantify temporal trends in HIV-attributable CVD burden at global, regional and...
Background: Lenacapavir is a first-in-class, long-acting HIV-1 capsid inhibitor enabling treatment and prevention with reduced reliance on daily oral adherence. Evidence from randomized trials across indications remains fragmented. We systematically...
Key take-home messages Developing culturally sensitive approaches and materials helps ensure HIV prevention interventions are relevant, acceptable, and responsive to the needs of the intended population groups. Close collaboration with...
Background Youth aged 15–24 years carry a disproportionate HIV/sexually transmitted infections (STIs) burden. In recent years, different modalities of digital health interventions (DHIs) have been explored to promote safer sex behaviors...
BACKGROUND: Chronic hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infections are among the most important global health issues. Virus-directed CAR-T and CAR-NK are promising strategies capable of targeting...
Background People living with HIV navigate complex medical and social challenges that impact engagement in care, including stigma, poverty and systemic inequities. Patient navigation has emerged as a promising approach...
Objective: To explore evidence on physical activity counseling for people living with HIV (PLHIV). Methods: Searches covered earliest records in PubMed (1946), Embase (1947), Web of Science (1900), Scopus (1788), and LILACS...
INTRODUCTION: HIV remains a major global public health challenge, with nearly 1.3 million new HIV acquisitions annually. Despite the effectiveness of pre-exposure (PrEP) and post-exposure prophylaxis (PEP), barriers to access,...
Background With the continuous advancement of various treatment modalities, such as antiretroviral therapy, the life expectancy of people living with HIV (PLWH) is approaching that of the general population. Consequently, the...
Background Unmet need for family planning remains a major challenge worldwide, particularly in Africa, contributing to unintended pregnancies, unsafe abortions, and increased maternal morbidity and mortality. Reducing the unmet need...
Background Ethical safeguards are critical in HIV research involving minors, especially vulnerable groups such as men who have sex with men (MSM) under 18 years. This systematic review explores how informed...
Background: HIV-related stigma among people living with HIV has emerged as a growing public health concern, yet limited longitudinal data are available to characterize its evolution over time. In this study,...
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