SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Youth advisory board engagement in HIV research in low- and middle-income countries: A scoping review and additional youth perspectives

2026

Background. Engaging young people (10–24 years old) in research has been shown to improve the uptake and impact of HIV interventions in youth. However, how youth are engaged in Youth...

Prevalence of loneliness and social isolation among people living with HIV: A systematic review and meta-analysis

2026

Design A systematic review and meta-analysis. Data Sources PubMed, Cochrane Library, SciELO Citation Index (via Web of Science), Scopus, Embase, PsycArticles, and Cumulative Index to Nursing and Allied Health Literature...

The impact of APOE ε4 on cognitive performance in adults with HIV: A systematic review and meta-analysis

2026

Objective: With a rapidly aging population living with HIV that may face a double-hit of neuroHIV and Alzheimer’s disease, the objective of this meta-analysis was to evaluate the impact of...

Effectiveness of friendship bench in alleviating anxiety and depression symptoms among people living with HIV and high-risk populations: A systematic review and meta-analysis

2026

This systematic review and meta-analysis evaluated the Friendship Bench (FB) intervention’s efficacy in relieving anxiety and depression among people living with HIV (PLHIV) and high-risk populations, explored intervention effect heterogeneity,...

Disparities in awareness, willingness and uptake of biomedical HIV prevention among bisexual and gay men: A systematic review and meta-analysis

2026

INTRODUCTION: The field of HIV/STI prevention research has primarily focused on gay men, leaving bisexual men overshadowed in broader discussions on sexual minority men’s health. Although also at increased risk...

Systematic scoping review on HIV services for males in Sub-Saharan Africa: Access, barriers, and research gaps

2026

BACKGROUND: Access to HIV services among men and boys in Sub-Saharan Africa is a significant public health challenge, exacerbated by cultural norms surrounding masculinity. This scoping review systematically investigates disparities...

Prevalence and associated factors of ICD/DSM-diagnosed depressive disorders among people living with HIV: A systematic review and meta-analysis

2026

Background: Depressive disorders are highly prevalent among people living with HIV (PLWH), severely impairing quality of life and antiretroviral therapy (ART) adherence. While ART advances call for reassessing depressive disorders among...

Strategies to improve PrEP adherence in people who use drugs: A systematic review

2026

People who use drugs (PWUD) face a disproportionately high risk of HIV, accounting for a considerable share of cases in the United States. Pre-exposure prophylaxis (PrEP) has been shown to...

Psychological distress experiences among patients living with HIV: A qualitative systematic review

2026

BACKGROUND: HIV patients endure psychological distress throughout the phases of diagnosis, treatment, and rehabilitation, which considerably affects their quality of life. A thorough comprehension of patients’ psychological distress experiences is...

Assessing the impact, barriers and facilitators of peer-driven interventions on the prevention of mother-to-child transmission of HIV in low- and middle-income countries: A systematic review and meta-analysis

2026

Introduction: Peer interventions may improve retention across the prevention of mother-to-child transmission (PMTCT) cascade in low- and middle-income countries (LMICs), where poor adherence to antiretroviral therapy (ART) remains a major barrier....

The benefit of physical exercise in improving quality of life, VO(2) max and sleep quality among older adults living with HIV: A systematic review and meta-analysis

2026

Background: Older adults living with HIV face multiple health challenges, yet evidence on the impact of exercise on their well-being remains limited. Regular physical activity is known to have multiple benefits...

Perinatal outcomes associated with antiretroviral therapy for pregnant women living with HIV: An umbrella review

2026

Background: The World Health Organization recommends antiretroviral therapy (ART) for pregnant women living with HIV (WLHIV), the vast majority of whom reside in sub-Saharan Africa. In recent years, many systematic reviews,...

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