SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Human immunodeficiency virus infection promotes human papillomavirus-mediated anal squamous carcinogenesis: An immunologic and pathobiologic review

2022

BACKGROUND: Anal squamous cell carcinoma (SCC) is a rare gastrointestinal malignancy with rising incidence, both in the United States and internationally. The primary risk factor for anal SCC is human...

Key population perceptions and opinions about long-acting antiretrovirals for prevention and treatment: A scoping review

2022

Purpose of review: Key populations are disproportionately affected by human immunodeficiency virus (HIV). Access, retention, and adherence are important barriers for the efficacy of preexposure prophylaxis (PrEP) and HIV treatment among...

National burden of intestinal parasitic infections and its determinants among people living with HIV/AIDS on anti-retroviral therapy in Ethiopia: A systematic review and meta-analysis

2022

Objectives: The aim of this systematic review and meta-analysis is designed to assess the pooled prevalence and determine risk factors of intestinal parasitic infections among people living with HIV/AIDS on anti-retroviral...

Efficacy of covid-19 vaccines in immunocompromised patients: Systematic review and meta-analysis

2022

Objective: To compare the efficacy of covid-19 vaccines between immunocompromised and immunocompetent people. Design: Systematic review and meta-analysis. Data sources: PubMed, Embase, Central Register of Controlled Trials, COVID-19 Open Research Dataset Challenge (CORD-19),...

The effectiveness and characteristics of mHealth interventions to increase adolescent’s use of sexual and reproductive health services in sub-Saharan Africa: A systematic review

2022

BACKGROUND: mHealth innovations have been proposed as an effective solution to improving adolescent access to and use of Sexual and Reproductive Health (SRH) services; particularly in regions with deeply entrenched...

Impact of antiretroviral therapy on kidney disease in HIV infected individuals—A qualitative systematic review

2022

Kidney disease is the fourth most common cause of non-AIDS-related mortality in people living with HIV. Combination antiretroviral therapy (cART) remains the cornerstone of treatment. However, little is known about...

Central nervous system and neurodevelopmental outcomes of HIV + and HIV exposed children: A mini review of recent findings and lessons learned from the field

2022

There has been an increase in research looking at neurodevelopmental/neurologic outcomes of children living with HIV (Children LWHIV) and HIV exposed but uninfected children (HEU) during an era of ART....

Genital cytokines in HIV/human papillomavirus co-infection: A systematic review

2022

Cervical cancer is the fourth cancer in incidence and the third in mortality among women worldwide. Women living with HIV have a significantly increased risk of cervical cancer. The immune...

Where are the pregnant and breastfeeding women in new pre-exposure prophylaxis trials? The imperative to overcome the evidence gap

2022

Pregnant and breastfeeding populations are at substantial risk of acquiring HIV in some settings, yet are underrepresented in clinical trials of new pre-exposure prophylaxis (PrEP) agents. Several PrEP formulations are...

Anal and cervical human papillomavirus genotypes in women co-infected with human immunodeficiency virus: A systematic review

2022

Human papillomavirus (HPV) and human immunodeficiency virus (HIV) infections are sexually transmitted. There are several HPV genotypes and clinical manifestations. Determining which genotypes circulate worldwide and/or in specific geographic areas...

Reproductive decision-making of Black women living with HIV: A systematic review

2022

BACKGROUND: Black women living with HIV account for a higher proportion of new HIV diagnoses than other groups. These women experience restricted access to reproductive services and inadequate support from...

Incentive-based sexually transmitted and blood-borne infections screening in high-income countries: A systematic review

2022

BACKGROUND: Despite increasing access to treatment and screening, rates of sexually transmitted and blood-borne infections (STBBI) continue to rise in high-income countries. The high cost of undiagnosed and untreated STBBI...

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