SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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HIV prevention interventions for men who have sex with men

2026

Key take-home messages

Virologic suppression among HIV-positive pregnant and lactating women receiving antiretroviral therapy in Africa: A systematic review and meta-analysis

2026

Background The elimination of mother-to-child transmission of human immunodeficiency virus (HIV) is a key global public health priority. In Africa, virologic failure among people living with HIV continues to pose a...

Alternative administration of antiretroviral therapy in people with HIV unable to swallow: A scoping review

2026

PURPOSE: To review published evidence on alternative administration methods for antiretroviral therapy in patients unable to swallow tablets. METHODS: We conducted a scoping review using PubMed, Web of Science, and...

Leveraging the barriers and facilitators of pre-exposure prophylaxis (PrEP) care among Latino men who have sex with men in the U.S. to inform intervention: A systematic literature review (2018–2023)

2026

HIV disproportionately affects Latino men who have sex with men (LMSM) in the United States (U.S.). Pre-exposure prophylaxis (PrEP) reduces HIV transmission, but prescription and use rates remain low among...

Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications

2026

Dolutegravir underpins modern first- and second-line HIV treatment regimens; however, interindividual variability in its disposition and tolerability presents challenges for optimal use. This scoping review mapped current evidence on the...

The role of religion and spirituality in HIV prevention: A systematic literature review and network analysis

2026

Religion and spirituality play an important role in shaping attitudes, beliefs, social norms, and preventive behaviors related to Human Immunodeficiency Virus (HIV) prevention across diverse populations and cultural settings. This...

Exploring the potential of cognitive intra-individual variability in HIV care and research in adults with HIV: A concept analysis

2026

Cognitive intraindividual variability (IIV) refers to the variability in one’s ability to sustain consistent cognitive performance. This phenomenon is linked to the emergence of cognitive impairment and dementia. The aim...

HIV self-testing and clinician-administered testing in Southern Africa: A systematic review of programmatic outcomes

2026

Objective: In 2024, an estimated 5.3 million of 40.8 million people with HIV (PWH) globally were unaware of their status, with Southern Africa bearing the highest regional burden. This review synthesizes...

Incidence and predictors of loss to follow-up among adults on antiretroviral therapy in Ethiopia: A systematic review and meta-analysis of cohort studies

2026

Background Loss to follow-up (LTFU) from antiretroviral therapy (ART) remains a major public health concern worldwide, including in Ethiopia. However, nationally representative pooled cohort data on LTFU among adults receiving...

Models of care for women living with HIV in Europe: A scoping review

2026

INTRODUCTION: With the widespread availability of antiretroviral therapy, human immunodeficiency virus (HIV) has become a chronic condition requiring long-term, integrated care. Women with HIV experience distinct clinical, reproductive, and psychosocial...

The prevalence of anxiety disorders among people living with HIV in India: A systematic review and meta-analysis

2026

BACKGROUND: Globally, 301 million face anxiety disorders, notably common among people living with human immunodeficiency virus (PLHIV), causing major challenges and reduced quality of life. AIM: This review assesses India’s...

Body image and its associated factors among people living with HIV: A scoping review and implications for integrated care

2026

People living with HIV (PLWH) face unique biopsychosocial challenges due to both infection and antiretroviral therapy (ART), one of which is body image disruption. This study comprehensively reviewed relevant studies...

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