SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Incidence and predictors of opportunistic infection among people living with HIV in Ethiopia: A systematic review and meta-analysis

2026

Background Opportunistic infections (OIs) play a crucial role in the morbidity and mortality of HIV‐infected individuals. Despite the increasing use of antiretroviral therapy, there remains a lack of comprehensive data...

Guidance on the clinical management of HIV-1 persistent low-level viraemia on antiretroviral treatment: A scoping review and an international Delphi consensus

2026

Despite the success of antiretroviral therapy, a subset of people with HIV experience low-level viraemia (LLV), a challenging condition with inconsistent definitions and management across settings. We conducted a scoping...

Strategies to integrate non-communicable disease interventions in HIV and tuberculosis care contexts in low- and middle-income countries: A scoping review

2026

INTRODUCTION: Integration of management of tuberculosis (TB) and HIV with prevention and treatment of non-communicable diseases (NCDs) is a global priority. However, delivering the full spectrum of HIV/TB and NCD...

Syndemics and clinical impact of HIV and mental health conditions among people living with HIV: A systematic review and meta-analysis

2026

INTRODUCTION: People living with HIV (PLWH) may be exposed to harmful political, social, economic and environmental factors that exacerbate their risk of mental health conditions. Such factors can interact synergistically...

Incidence of occupational HIV seroconversion among healthcare workers: A systematic review and meta-analysis

2026

Background Healthcare workers (HCWs) may be at elevated risk of HIV infection due to the global HIV burden and frequent occupational exposure to blood and body fluids (BBF). This systematic...

Colorectal cancer screening uptake and lesion detection in people living with HIV: A systematic review and meta-analysis

2026

Introduction: As people living with HIV age, the absolute colorectal cancer (CRC) burden rises, yet the extent of routine CRC screening delivery and clinical yield is unclear. We synthesized evidence on...

Prevalence and risk factors for cytomegalovirus retinitis among people living with HIV in sub-Saharan Africa in the antiretroviral therapy era: A systematic review and meta-analysis

2026

Cytomegalovirus retinitis has remained an alarming and potentially vision-threatening opportunistic disease in the population living with HIV, especially in cases of extreme immunosuppression. Although the introduction of antiretroviral therapy has...

Prevalence of fungemia in people with HIV: A systematic review and meta-analysis

2026

Prior to the introduction of antiretroviral therapy (ART), people with HIV (PWH) had high risk of fungemia. No systematic review has assessed the prevalence of fungemia in PWH after the...

Closing diagnostic gaps in pediatric HIV: Innovations in point-of-care and digital monitoring with an Asia-Pacific implementation lens—A systematic review

2026

Background/Objectives: Pediatric HIV case-finding and monitoring remain constrained by delayed early infant diagnosis (EID), loss to follow-up, and limited viral load (VL) testing-challenges particularly consequential in the operationally diverse Asia-Pacific...

Evaluating the effectiveness of digital health interventions for HIV prevention and treatment adherence among transgender populations: A systematic review and meta-analysis

2026

Background Transgender individuals face a disproportionate burden of HIV due to systemic barriers including stigma, discrimination, and limited access to gender-affirming healthcare. Digital health interventions (DHIs), such as mobile applications,...

Lived experiences of cancer care for people living with HIV who are treated for anal cancer: A scoping review

2026

OBJECTIVE: This scoping review aims to identify existing evidence on the lived experiences of people living with HIV and treated for anal cancer, and to identify what aspects of health...

Burden of malaria-HIV coinfection and associated adverse outcomes in Ethiopia: A systematic review and meta-analysis

2026

Background The co-occurrence of malaria and HIV represents a significant health crisis in sub-Saharan Africa, particularly in Ethiopia, where both diseases are prevalent. This synergistic burden aggravates health inequalities, strains...

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