SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Physical activity counseling for people living with HIV: A scoping review

2026

Objective: To explore evidence on physical activity counseling for people living with HIV (PLHIV). Methods: Searches covered earliest records in PubMed (1946), Embase (1947), Web of Science (1900), Scopus (1788), and LILACS...

Role of pharmacists in HIV prophylaxis: A scoping review of pharmacists’ services, interventions and outcomes

2026

INTRODUCTION: HIV remains a major global public health challenge, with nearly 1.3 million new HIV acquisitions annually. Despite the effectiveness of pre-exposure (PrEP) and post-exposure prophylaxis (PEP), barriers to access,...

Effectiveness and safety of darunavir and lopinavir for treating children and adolescents living with HIV: A systematic review

2026

Introduction Darunavir and lopinavir solid formulations are recommended protease inhibitors for treating HIV. An evidence review of their effectiveness/efficacy and safety in young populations was needed to inform the 2025...

Global mental health disparities among transgender women and transfeminine people living with HIV: A systematic review and meta-analysis of 63 studies

2026

Background Transgender women and transfeminine people face a disproportionate burden of mental health conditions driven by stigma, discrimination, and structural inequities, with additional psychosocial challenges related to HIV diagnosis and...

Efficacy and safety of TDF+3TC + EFV-centric antiretroviral regimens for HIV/HBV co-infection: A systematic review and network meta-analysis

2026

Objective To evaluate the efficacy and safety of antiretroviral therapy(ART) regimens based on tenofovir(TDF) + lamivudine(3TC) + efavirenz(EFV) in patients co-infected with Human Immunodeficiency Virus (HIV) and Hepatitis B Virus...

Integration of HIV, Hepatitis B, and C, and sexually transmitted infections services: A scoping review of the benefits and challenges

2026

BACKGROUND: Integrating clinical programs and services is a cost-effective approach that can improve health and system outcomes. This review aimed to provide an overview of the benefits and challenges of...

Effectiveness of digital health interventions on antiretroviral therapy adherence among people living with HIV in India: A systematic review with an RCT-only meta-analysis

2026

The widespread use of combination antiretroviral therapy has transformed HIV infection into a chronic condition, with life expectancy of people with HIV (PWH) approaching that of the general population when...

Efficacy and safety of long-acting lenacapavir for HIV treatment and prevention: A systematic review of randomized trials

2026

Background: Lenacapavir is a first-in-class, long-acting HIV-1 capsid inhibitor enabling treatment and prevention with reduced reliance on daily oral adherence. Evidence from randomized trials across indications remains fragmented. We systematically...

Culturally competent HIV prevention for African, Caribbean, and Black communities and Indigenous Peoples

2026

Key take-home messages Developing culturally sensitive approaches and materials helps ensure HIV prevention interventions are relevant, acceptable, and responsive to the needs of the intended population groups. Close collaboration with...

Burden and clinical impact of ‘neglected’ transfusion-transmitted infections in Cameroon: A systematic review and meta-analysis

2026

Background Blood supply is a public health challenge in African countries. In Cameroon, blood selection guidelines focus on four viral and bacterial pathogens (HIV, hepatitis B and C viruses, Treponema pallidum)...

Assessing the state of published HIV research concerning sexual minority women: A global English language scoping review

2026

PURPOSE: We conducted a scoping review to map peer-reviewed literature on HIV research concerning sexual minority women (SMW). METHODS: Following guidance from Arksey and O’Malley’s framework and the Preferred Reporting...

Success rate of dental implants in HIV patients: An overview of systematic reviews

2026

AIMS: To identify whether individuals with positive serology for HIV have a higher risk of losing the dental implant for this treatment. METHODS AND RESULTS: This study was conducted according...

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