SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Examining the relationship between HIV-related stigma and the health and wellbeing of children and adolescents living with HIV: A systematic review

2023

Human immunodeficiency virus (HIV) affects millions of people globally. The associated stigma remains a challenge for individuals living with HIV and children and adolescents face the additional challenge of withstanding...

Effectiveness of behavioural economics informed interventions for the prevention, screening, and antiretroviral treatment of HIV infection: A systematic review of randomized controlled trials

2023

Failure to meet international targets set for the human immunodeficiency virus HIV pandemic suggests that more effective public health strategies are needed. New strategies informed by behavioural economics are now...

Coronavirus (COVID-19) and sexualised drug use among men who have sex with men: A systematic review

2023

Drug-related harms, including harms from sexualised drug use (SDU), are disproportionately experienced by sexual and gender minority people, relative to their majority counterparts. Chemsex, a type of SDU practiced mainly...

Antivirals for prevention of hepatitis B virus mother-to-child transmission in human immunodeficiency virus positive pregnant women co-infected with hepatitis B virus

2023

BACKGROUND: Hepatitis B virus (HBV)-human Immunodeficiency virus (HIV) co-infection promotes an aggressive disease course of HBV infection. In the only available non-Cochrane systematic review on antiviral therapy during pregnancy for...

The association between HIV diagnosis disclosure and adherence to anti-retroviral therapy among adolescents living with HIV in Sub-Saharan Africa: A systematic review and meta-analysis

2023

INTRODUCTION: Nine in ten of the world’s 1.74 million adolescents living with human immunodeficiency virus (ALHIV) live in Sub-Saharan Africa. Suboptimal adherence to antiretroviral therapy (ART) and poor viral suppression...

Determining the screening frequency for sexually transmitted infections for people who use HIV pre-exposure prophylaxis: A systematic review and meta-analysis

2023

Background: Although the World Health Organization (WHO) recommends ‘frequent’ screening of sexually transmitted infections (STI) for people who use pre-exposure prophylaxis (PrEP) for HIV, there is no evidence for optimal frequency....

Performance of cardiovascular risk prediction models among people living with HIV: A systematic review and meta-analysis

2023

Importance  Extant data on the performance of cardiovascular disease (CVD) risk score models in people living with HIV have not been synthesized. Objective  To synthesize available data on the performance of the...

Immunogenicity, effectiveness and safety of SARS-CoV-2 vaccination in people living with HIV: A systematic review and meta-analysis

2023

Objectives: People living with HIV (PLWH) experience a greater risk of morbidity and mortality following COVID-19 infection, and poorer immunological responses to several vaccines. We explored existing evidence regarding the immunogenicity,...

Characteristics of psychosocial interventions to improve ART adherence in people living with HIV: A systematic review

2023

The HIV/AIDS pandemic continues to be a significant global public health crisis. The main HIV/AIDS treatment is the antiretroviral therapy (ART), which is highly effective but depends on the patient’s...

Performance of HIV infection prediction models in men who have sex with men: A systematic review and meta-analysis

2023

Effective ways to identify and predict men who have sex with men (MSM) at substantial risk for HIV is a global priority. HIV risk assessment tools can improve individual risk...

Pharmacotherapeutic interventions in people living with HIV undergoing solid organ transplantation: A scoping review

2023

The pharmacotherapeutic management of people living with HIV (PLWHIV) undergoing solid organ transplantation (SOT) is clinically challenging, mainly due to the frequent occurrence of complex drug-drug interactions. Although various strategies...

Undetectable=Untransmittable=Universal Access (U=U=U): Transforming a foundational, community-led HIV/AIDS health informational advocacy campaign into a global HIV/AIDS health equity strategy and policy priority

2023

BACKGROUND: Undetectable=Untransmittable (U=U) first emerged in 2016 as a health information campaign to promote rigorous scientific evidence that people living with HIV (PLHIV) on effective treatment who have reached an...

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