SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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The prevalence and influencing factors of frailty among middle-aged and older adults with HIV/AIDS from a global perspective: A systematic review and meta-analysis

2026

Aim: Currently, frailty has become a central issue in health management among middle-aged and older people living with HIV/AIDS (PLWHA) worldwide. The objective is to develop targeted strategies to improve frailty...

The global epidemiology of injecting drug use, HIV, viral hepatitis and tuberculosis among people who are incarcerated: A multistage systematic review

2026

Background: This global systematic review assesses the prevalence of injecting drug use (IDU) and key infectious diseases (HIV, hepatitis C virus [HCV], tuberculosis and hepatitis B virus [HBV]) among people...

Relationship quality among people living with HIV/AIDS: A systematic review and meta-analysis

2026

Background The aim of this systematic review and meta-analysis was to summarize the existing literature on the factors associated with relationship quality among people living with HIV (PLWH). Method A...

Usable access to HIV testing and care among people with migrant backgrounds in Japan: A systematic review

2026

OBJECTIVES: Japan’s growing migrant population has increased the need for HIV services usable across linguistic, administrative and social circumstances. We reviewed evidence on access to HIV testing and care among...

Condom use and associated factors among people living with HIV/AIDS on anti-retroviral therapy (ART) in Ethiopia: A systematic review and meta-analysis

2026

Condom use remains a crucial preventive measure for individuals undergoing antiretroviral therapy (ART) in the fight against HIV/AIDS. This review and meta-analysis aimed to determine the pooled prevalence of condom...

Dysregulated metabolism in people living with HIV in the modern ART-era: A systematic review of targeted metabolomics studies

2026

HIV remains a significant public health issue, with 1.3 million new infections and 630,000 deaths annually, and 40.8 million people living with HIV (PLHIV) globally in 2024. Although antiretroviral therapy...

HIV prevention interventions for men who have sex with men

2026

Key take-home messages

Virologic suppression among HIV-positive pregnant and lactating women receiving antiretroviral therapy in Africa: A systematic review and meta-analysis

2026

Background The elimination of mother-to-child transmission of human immunodeficiency virus (HIV) is a key global public health priority. In Africa, virologic failure among people living with HIV continues to pose a...

Alternative administration of antiretroviral therapy in people with HIV unable to swallow: A scoping review

2026

PURPOSE: To review published evidence on alternative administration methods for antiretroviral therapy in patients unable to swallow tablets. METHODS: We conducted a scoping review using PubMed, Web of Science, and...

Leveraging the barriers and facilitators of pre-exposure prophylaxis (PrEP) care among Latino men who have sex with men in the U.S. to inform intervention: A systematic literature review (2018–2023)

2026

HIV disproportionately affects Latino men who have sex with men (LMSM) in the United States (U.S.). Pre-exposure prophylaxis (PrEP) reduces HIV transmission, but prescription and use rates remain low among...

Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications

2026

Dolutegravir underpins modern first- and second-line HIV treatment regimens; however, interindividual variability in its disposition and tolerability presents challenges for optimal use. This scoping review mapped current evidence on the...

The role of religion and spirituality in HIV prevention: A systematic literature review and network analysis

2026

Religion and spirituality play an important role in shaping attitudes, beliefs, social norms, and preventive behaviors related to Human Immunodeficiency Virus (HIV) prevention across diverse populations and cultural settings. This...

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