SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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The influence of viral protein R amino acid substitutions on clinical outcomes in people living with HIV: A systematic review

2023

BACKGROUND: The HIV viral protein R (Vpr) is a multifunction protein involved in the pathophysiology of HIV-1. Recent evidence has suggested that Vpr amino acid substitutions influence the pathophysiology of...

Diagnosis, treatment, and prevention of HIV infection among detainees: A review of the literature

2022

Detainees are one of the most vulnerable populations to human immunodeficiency virus (HIV). This is mostly caused by the lack of knowledge on the topic among the inmates; the lack...

Web-based service provision of HIV, viral hepatitis, and sexually transmitted infection prevention, testing, linkage, and treatment for key populations: Systematic review and meta-analysis

2022

BACKGROUND: Despite the growth of web-based interventions for HIV, viral hepatitis (VH), and sexually transmitted infections (STIs) for key populations, the evidence for the effectiveness of these interventions has not...

The prevalence of HIV infection in minority Indigenous populations of the South-East Asia and Western Pacific regions: A systematic review and meta-analysis

2022

A random effects meta-analysis was used to estimate the pooled prevalence of HIV infection within minority indigenous populations of the South-East Asia (SEAR) and Western Pacific Regions (WPR). Sub-group analyses...

Multilevel model in the identification of behavioral and structural risk factors for HIV: integrative review

2023

OBJECTIVES: to investigate studies that adopted the multilevel analysis model to identify behavioral and structural risk factors associated with HIV infection. METHODS: an integrative review of the literature with studies...

A scoping review on COVID-19 vaccine hesitancy among the lesbian, gay, bisexual, transgender, queer, intersex and asexual (LGBTQIA+) community and factors fostering its refusal

2023

BACKGROUND: The ramifications of the existing crisis caused by the coronavirus pandemic are sensed in all walks of life. Among the various efforts made to curb the spread of this...

Ageing with HIV: Medicine optimisation challenges and support needs for older people living with HIV: A systematic review

2023

Background: Older people living with HIV (PLWH) are at increased risks of co-morbidities and polypharmacy. However, little is known about factors affecting their needs and concerns about medicines. This systematic review...

Mental health problems across the HIV care continuum for adolescents living with HIV in sub-Saharan Africa: A scoping review

2023

Mental health problems (e.g., anxiety, depression) are frequently experienced by adolescents living with HIV (ALWH) and can worsen HIV-related outcomes. This scoping review synthesizes the existing research on ALWHs’ mental...

The mother-to-child transmission of HIV-1 and profile of viral reservoirs in pediatric population: A systematic review with meta-analysis of the Cameroonian studies

2023

Background: The mother-to-child transmission of HIV-1 (MTCT) remains on the major route of HIV-transmission among pediatric populations in Africa. Though a prevention of MTCT (PMTCT) high-priority country, data on the MTCT...

A qualitative systematic literature review of the role of U.S. pharmacists in prescribing pre-exposure prophylaxis (PrEP)

2023

Pre-Exposure Prophylaxis (PrEP) is an effective treatment to combat the human immunodeficiency virus (HIV) endemic, but the uptake of PrEP has been low in the United States (U.S.). While individuals...

Universal health coverage for antiretroviral treatment: A review

2023

Universal health coverage is essential for the progress to end threats of the acquired immunodeficiency syndrome epidemic. The current review assesses the publication rate, strategies and barriers for antiretroviral therapy...

Virological failure and adherence to antiretroviral therapy in adolescents and young adults living with human immunodeficiency virus

2023

Objective: HIV (human immunodeficiency virus) infection remains a major public health challenge. Infected young people at any age are less likely to adhere to care in a timely manner and to...

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