SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Global coverage of interventions for reduction of injecting drug use-related harm, HIV, viral hepatitis and tuberculosis in prisons and other carceral settings: A systematic review

2026

BACKGROUND: People who are incarcerated experience disproportionately high rates of injecting drug use and infectious disease, including HIV, viral hepatitis and tuberculosis. However, comprehensive global data regarding the availability of...

Strategies to integrate non-communicable disease interventions in HIV and tuberculosis care contexts in low- and middle-income countries: A scoping review

2026

INTRODUCTION: Integration of management of tuberculosis (TB) and HIV with prevention and treatment of non-communicable diseases (NCDs) is a global priority. However, delivering the full spectrum of HIV/TB and NCD...

A systematic review and meta-analysis on the association between antiretroviral therapy refill type and viral suppression

2026

To reduce barriers to viral suppression, people living with HIV (PLWH) are placed on multi-month dispensing (MMD)of antiretroviral therapy medication. However, there are concerns about viral rebound following MMD initiation,...

Effectiveness of mobile health (mHealth) interventions on ART adherence among people living with HIV in low- and middle-income countries: A systematic review and meta-analysis

2025

Antiretroviral therapy (ART) is essential for HIV treatment, yet maintaining high adherence remains challenging in resource-limited settings. Mobile health (mHealth) interventions offer a scalable approach to support adherence. This meta-analysis...

Youth advisory board engagement in HIV research in low- and middle-income countries: A scoping review and additional youth perspectives

2026

Background. Engaging young people (10–24 years old) in research has been shown to improve the uptake and impact of HIV interventions in youth. However, how youth are engaged in Youth...

Prevention of mother-to-child transmission of HIV in the MENA region: A systematic review with comparative evidence from sub-Saharan Africa

2026

The Middle East and North Africa (MENA) region faces distinct challenges in addressing the HIV epidemic, including social stigma, limited surveillance data, and insufficient coverage of prevention services. Prevention of...

Effects of transition from paediatric to adult HIV care on virological outcomes in sub-Saharan Africa: A systematic review and meta-analysis

2026

Background: HIV remains a major global burden, with 2.4 million children and adolescents affected, 84% living in sub-Saharan Africa. As adolescents age, transitioning from paediatric to adult HIV care represents a...

Factors influencing implementation of point-of-care tests for maternal and newborn screening and diagnosis in low-resource settings: A systematic review

2026

BACKGROUND: Despite the potential of point-of-care (POC) tests to improve maternal and newborn health, implementation in low- and middle-income countries remains inconsistent. POC testing enables rapid, decentralized screening, but barriers...

The vaginal microbiome of pregnant people living with HIV on antiretroviral therapy in the Democratic Republic of Congo: A pilot study and global meta-analysis

2026

Recent studies reveal that a suboptimal vaginal microbiome (VMB), including the enrichment of anaerobic bacteria associated with multiple female genital disorders, is linked to adverse pregnancy and birth outcomes in...

Rifapentine-isoniazid versus isoniazid-alone therapy for tuberculosis prevention among people living with HIV (PLHIV): A systematic review and meta-analysis of randomized trials

2026

Introduction Tuberculosis (TB), a substantial cause of morbidity and mortality among people living with human immunodeficiency virus (PLHIV), accounted for 161,000 deaths among HIV-co-infected patients in 2023. Tuberculosis preventive therapy...

Rapid diagnostic tests, laboratory-based immunoassay and nucleic acid testing strategies for long-acting injectable pre-exposure prophylaxis: A systematic review and meta-analysis

2026

Background Long-acting injectable pre-exposure prophylaxis (LAI-PrEP) is a highly effective biomedical intervention for the prevention of HIV acquisition. There is a strong interest among communities and policymakers for LAI-PrEP scale-up,...

The gap in integrated pediatric care: A systematic review of family-based weight management for children living with HIV

2026

BACKGROUND: As children living with HIV (CWH) achieve longer life expectancy, they face an emerging ‘double burden’ of infectious and non-communicable diseases, specifically pediatric overweight and obesity (OW/OB). This risk...

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