SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Understanding HIV-exposed uninfected children: A narrative review

2025

The widespread implementation of antiretroviral therapy has significantly reduced HIV-related mortality and mother-to-child transmission. Despite being HIV-uninfected, HIV-exposed children (HEU) seem to face heightened risks of immune dysfunction, cardiometabolic diseases,...

Burden of depression among HIV caregivers in India: A systematic review and meta-analysis

2025

Caregivers of individuals living with HIV face significant mental health challenges, with depression being the most common. Despite global research highlighting this burden, studies specific to the Indian context are...

Evidence on digital HIV self-testing from accuracy to impact: Updated systematic review

2025

BACKGROUND: HIV self-testing has gained momentum following the approval of self-testing methods and novel technological advancements. Digital HIV self-testing involves completing an oral or blood-based HIV self-test with support from...

Depressive symptoms and its determinants among people living with HIV in Africa: Systematic review and meta-analysis

2025

Background: In Africa, depressive symptoms are prevalent among people living with HIV (PLHIV), significantly impacting their adherence and overall quality of life. The combined burden of HIV and depressive symptoms worsens...

HIV risk score and prediction model in the United States: A scoping review

2025

Human immunodeficiency virus (HIV) remains a public health issue in the U.S., affecting approximately 1.2 million individuals, many of whom are unaware of their infection status. This study reviews predictors...

Urgent focus on the surgical risks of people living with HIV: A systematic review and meta-analysis

2025

With the widespread promotion and application of antiretroviral therapy in clinical practice, people living with HIV (PLWH) have the potential to live as long as non-HIV people and the probability...

Effect of maternal HIV infection on birth outcomes among HIV positive women in Sub Saharan Africa: A systematic review and meta-analysis

2025

BACKGROUND: HIV is remaining the public health issues with an estimated of 39 million peoples are living with the virus till 2022. HIV positive pregnant women are at a greater...

Risk factors and mortality outcomes of COVID-19 in people living with HIV: A systematic review and meta-analysis

2024

This study was performed to reveal the risk factors associated with mortality in people living with HIV (PLHIV) who were diagnosed with COVID-19. Studies reporting deaths among PLHIV and infected...

HIV infection and esophageal cancer in sub-Saharan Africa: A comprehensive meta-analysis

2024

Africa hosts the highest burden of esophageal cancer (49%) and HIV (60%) worldwide. It is imperative to investigate the synergistic impact of these two diseases on African populations. This study...

Global epidemiology of HIV among dialysis patients: A systematic review and meta-analysis

2025

HIV transmission and infection among dialysis patients have become a major healthcare concern and a rising threat throughout the world. Our current systematic review and meta-analysis targeted to determine the...

Predictors of anemia among HIV-infected children in Ethiopia: Systematic review and meta-analysis

2025

Anemia continues to be one of the common complications among HIV-infected children. In Ethiopia, though there is a systematic review and meta-analysis study on anemia among HIV-infected children, it only...

HIV-1 resistance and virological failure to treatment with the integrase inhibitors bictegravir, cabotegravir, and dolutegravir: A systematic literature review

2024

We describe and analyze resistance-associated mutations (RM) and virological failures (VF) on antiretroviral therapy using the latest approved integrase inhibitors (INIs) dolutegravir (DTG), bictegravir (BIC), and cabotegravir (CAB), together with...

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