SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Risk of HIV transmission by healthcare workers—A systematic review

2026

BACKGROUND: Occupational HIV infection among healthcare workers (HCWs) has declined markedly in high-income countries as a result of improved infection prevention and control, safety-engineered devices, and the widespread availability of...

International guidelines for the management of healthcare workers living with HIV: A systematic comparative review

2026

BACKGROUND: Despite strong evidence that sustained HIV viral suppression eliminates transmission risk (“undetectable equals untransmittable”, U=U), national approaches to managing healthcare workers (HCWs) living with HIV remain heterogeneous. Because such...

HIV prevalence in transgender women and cisgender men who have sex with men in sub-Saharan Africa

2025

Introduction: The Global AIDS Strategy 2021–2026 calls for equitable access to HIV services for all populations. Transgender people have been marginalized and experience disproportionate risk of HIV infection in sub-Saharan...

Unmet need for family planning among reproductive-age women living with HIV in Africa: a systematic review and meta-analysis

2026

No abstract available

Telomere length dynamics in adults living with HIV: A systematic review

2026

Background: HIV infection is associated with accelerated biological ageing, with telomere shortening serving as a key biomarker. Although numerous studies have investigated telomere dynamics in people living with HIV (PLWH),...

The global epidemiology of injecting drug use, HIV, viral hepatitis and tuberculosis among people who are incarcerated: A multistage systematic review

2026

Background: This global systematic review assesses the prevalence of injecting drug use (IDU) and key infectious diseases (HIV, hepatitis C virus [HCV], tuberculosis and hepatitis B virus [HBV]) among people...

Syndemics and clinical impact of HIV and mental health conditions among people living with HIV: a systematic review and meta-analysis

2026

INTRODUCTION: People living with HIV (PLWH) may be exposed to harmful political, social, economic and environmental factors that exacerbate their risk of mental health conditions. Such factors can interact synergistically...

Experiences and outcomes of peer navigation and support interventions for adolescents on HIV treatment in sub-Saharan Africa: A qualitative evidence synthesis

2026

Adolescents living with HIV (ALHIV) face ongoing challenges with treatment adherence and engagement in care, resulting in lower viral suppression rates compared to adults. Peer navigation has shown promise in...

Strategies to improve PrEP adherence in people who use drugs: A systematic review

2026

People who use drugs (PWUD) face a disproportionately high risk of HIV, accounting for a considerable share of cases in the United States. Pre-exposure prophylaxis (PrEP) has been shown to...

Patients’ perspectives on medication adherence feedback interventions for managing long-term medications: A systematic review of qualitative evidence

2026

INTRODUCTION: Optimising medication usage is a worldwide challenge. While numerous feedback interventions have been developed to address this issue, understanding patients’ perspectives on the use of such interventions to optimise...

Strategies to integrate non-communicable disease interventions in HIV and tuberculosis care contexts in low- and middle-income countries: a scoping review

2026

INTRODUCTION: Integration of management of tuberculosis (TB) and HIV with prevention and treatment of non-communicable diseases (NCDs) is a global priority. However, delivering the full spectrum of HIV/TB and NCD...

Rifapentine-isoniazid versus isoniazid-alone therapy for tuberculosis prevention among people living with HIV (PLHIV): a systematic review and meta-analysis of randomized trials

2026

INTRODUCTION: Tuberculosis (TB), a substantial cause of morbidity and mortality among people living with human immunodeficiency virus (PLHIV), accounted for 161,000 deaths among HIV-co-infected patients in 2023. Tuberculosis preventive therapy...

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