SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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A systematic literature review on pre-exposure prophylaxis as a strategy for HIV risk reduction in the Middle East

2025

Pre-exposure prophylaxis (PrEP) has emerged as a crucial tool in HIV prevention globally, yet its implementation in the Middle East and North Africa (MENA) region faces unique challenges. PrEP is...

Health service utilization of Black immigrant women residing in the United States: A systematic review

2024

Black immigrants constitute a rapidly growing population group in the U.S. A comprehensive understanding of health services used by Black immigrant women is necessary to support the complex needs of...

Improving communication: A narrative synthesis of interventions for HIV disclosure to pediatric populations

2025

PURPOSE OF REVIEW: HIV remains a significant global public health concern, affecting millions worldwide, including children. Disclosure of HIV status to infected children holds several benefits, yet rates of disclosure...

Prevalence of HHV-6 detection among people living with HIV: A systematic review and meta-analysis

2025

Human herpesvirus 6 (HHV-6) is a ubiquitous virus with significant implications for immunocompromised individuals, particularly people living with HIV (PLWH). This study aimed to estimate the prevalence of HHV-6 detection...

Experiences of older people living with human immunodeficiency virus comorbidity attending coordinated healthcare services

2025

BACKGROUND: Older people living with human immunodeficiency virus (OPLWHIV) on antiretroviral therapy are aging and face an increased risk of non-communicable diseases. The burden is costly and demands sustainable care...

Breast cancer clinical characteristics, management, and outcomes in women living with HIV/AIDS globally: A systematic review and meta-analysis

2025

Although associations between HIV and breast cancer (BC) have been investigated, the global literature remains inconsistent regarding clinical features and outcomes in HIV-positive patients. This study aims to clarify the...

An international compendium of health state utilities in people with HIV: A systematic review

2025

Purpose: Measuring health-related quality of life across different health states for people with HIV (PWH) using direct or indirect preference-based values can inform decision-analytic models evaluating cost-effectiveness of different care strategies....

Ptosis in human immunodeficiency virus-infected patients under long-term antiretroviral treatment

2024

OBJECTIVE: To present cases of ptosis in HIV-1 patients on long-term antiretroviral therapy (ART) and review the existing literature. METHODS: Five HIV-1-positive patients with slowly progressive bilateral ptosis underwent a...

Clinical trials of broadly neutralizing monoclonal antibodies in people living with HIV—A review

2025

Introduction HIV-1 remains a major global health challenge, impacting approximately 39 million people worldwide. Although antiretroviral therapy has substantially reduced HIV incidence and enhanced the quality of life for those living...

Exercise interventions conducted among individuals with co-occurring HIV and unhealthy substance use: A systematic review

2025

Unhealthy substance use and physical inactivity are prevalent co-occurring risk factors for morbidity and mortality among people with HIV (PWH). Evidence-based exercise interventions targeting both risk factors are limited. We...

Global, regional, and national estimates of hepatitis C virus (HCV) infection incidence among people who inject drugs and number of new annual HCV infections attributable to injecting drug use: A multi-stage analysis

2025

Background: Measuring progress towards the WHO 2030 target for hepatitis C virus (HCV) elimination among people who inject drugs (PWID)-an incidence of two or fewer infections per 100 person-years-has been challenging...

Body image among people living with HIV: A systematic review and narrative synthesis

2025

OBJECTIVES: The aim of this systematic review was to analyse, synthesise and review existing research on body image among people living with HIV (PLWH). Specifically, the review investigated the relationship...

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