SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Found 2246 matching articles (Displaying on 188 pages)

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Perinatal outcomes among pregnant women with HIV initiating antiretroviral therapy preconception and antenatally

2024

OBJECTIVE: Increasingly, pregnant women with HIV (WHIV) initiate antiretroviral therapy (ART) before conception. We assessed the risk of adverse perinatal outcomes among pregnant WHIV initiating ART preconception or antenatally, compared...

Experiences of older people living with human immunodeficiency virus comorbidity attending coordinated healthcare services

2025

BACKGROUND: Older people living with human immunodeficiency virus (OPLWHIV) on antiretroviral therapy are aging and face an increased risk of non-communicable diseases. The burden is costly and demands sustainable care...

Gastrointestinal Escherichia coli in men who have sex with men: A systematic review

2024

OBJECTIVE: This systematic review aimed to explore any demographic, biological and behavioural characteristics of men who have sex with men (MSM) with diarrhoeagenic E.coli. DESIGN/METHODS: We searched MEDLINE, EMBASE, and...

Ptosis in human immunodeficiency virus-infected patients under long-term antiretroviral treatment

2024

OBJECTIVE: To present cases of ptosis in HIV-1 patients on long-term antiretroviral therapy (ART) and review the existing literature. METHODS: Five HIV-1-positive patients with slowly progressive bilateral ptosis underwent a...

Prevalence of HHV-6 detection among people living with HIV: A systematic review and meta-analysis

2025

Human herpesvirus 6 (HHV-6) is a ubiquitous virus with significant implications for immunocompromised individuals, particularly people living with HIV (PLWH). This study aimed to estimate the prevalence of HHV-6 detection...

INSTIs-centered antiviral regimens for first-line treatment of HIV/AIDS: A network meta-analysis and cost-effectiveness analysis

2025

OBJECTIVE: This study evaluates the efficacy, safety, and cost-effectiveness of INSTI-based antiretroviral regimens compared to the national standard first-line treatment EFV/3TC/TDF for HIV/AIDS in China. The aim is to guide...

Gender-based violence syndemics in global health: A systematic review

2025

Global guidance indicates that protections for gender and equity issues, such as gender-based violence (GBV), should be mainstreamed across sectors. One novel strategy that can be leveraged to illustrate the...

Transition to adult care for young people living with HIV

2025

Purpose of Review The purpose of this narrative review is to delineate the challenges of transitioning young people living with HIV (YPLHIV) to adult-based care and to review recent literature...

Clinical trials of broadly neutralizing monoclonal antibodies in people living with HIV—A review

2025

Introduction HIV-1 remains a major global health challenge, impacting approximately 39 million people worldwide. Although antiretroviral therapy has substantially reduced HIV incidence and enhanced the quality of life for those living...

The role of digital tools in enhancing antiretroviral therapy adherence among adolescents and young adults with HIV: A systematic review of randomized controlled trials

2025

Background: Adolescents and Young Adults (AYA) face challenges in maintaining antiretroviral therapy (ART) adherence, necessitating the need for targeted and innovative interventions. Digital tools have shown potential in improving ART adherence...

Exercise interventions conducted among individuals with co-occurring HIV and unhealthy substance use: A systematic review

2025

Unhealthy substance use and physical inactivity are prevalent co-occurring risk factors for morbidity and mortality among people with HIV (PWH). Evidence-based exercise interventions targeting both risk factors are limited. We...

Pre-exposure prophylaxis uptake among Black/African American men who have sex with other men in Midwestern, United States: A systematic review

2025

INTRODUCTION: Black/African American men who have sex with other men (BMSM) are disproportionately affected by HIV, experience significant disparities in HIV incidence, and face significant barriers to accessing HIV treatment...

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