SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Loneliness and social isolation in people with HIV

2025

PURPOSE OF REVIEW: Antiretroviral therapy (ART) has significantly extended the life expectancy of people with HIV (PWH). However, as this population ages, they face increased risk of social isolation and...

Incidence of adverse drug reactions among HIV patients on antiretroviral drugs in Ethiopia: A systematic review and meta-analysis

2025

Introduction: In recent decades, AIDS–related illnesses have declined due to the widespread use of highly active antiretroviral therapy (HAART). Despite the numerous benefits that HAART provides, it causes significant challenges for...

What are the risk factors of non-fatal overdose among persons who use opioids? A systematic review and meta-analysis

2025

Introduction: Non-fatal opioid overdose (NFOD) is a concerning public health issue that is a risk factor for subsequent fatal overdose. Methods: This systematic review aimed to evaluate all the previous literature using...

The prevalence of human papillomavirus (HPV) genotypes in the oral mucosae of HIV-positive individuals: A systematic review and meta-analysis

2025

Papillomaviruses are double-stranded DNA viruses, and it is essential to clarify their genotypic distribution for their effective prevention and clinical management. In this study, we aimed to evaluate the prevalence...

Efficacy of long-acting cabotegravir plus rilpivirine in viraemic people living with HIV: A systematic review and meta-analysis

2025

BACKGROUND: Long-acting cabotegravir/rilpivirine (LA-CAB/RPV) is currently approved as a switch strategy in people living with HIV virally suppressed on oral antiretroviral therapy. Although small reports on specific, difficult-to-treat populations demonstrated...

Evidence from high-income countries on the effectiveness of psychosocial interventions to improve mental health, wellbeing and quality of life for adults living with HIV: A systematic review and meta-analysis

2025

INTRODUCTION: There is a need to synthesize recent evidence on the effectiveness of psychosocial interventions to improve mental health, quality of life and wellbeing in adults living with HIV in...

A rapid review of HIV-related stigma-reduction randomized controlled trials

2025

We conducted a rapid review to identify and describe randomized controlled trials (RCTs) aimed at reducing HIV-related stigma. Using a rapid review design in accordance with PRISMA guidelines, we searched...

Growth and body composition of adolescents and young adults with perinatal HIV infection: A systematic review and meta-analysis

2025

Introduction: Approximately 1.3 million pregnancies are exposed to HIV perinatally each year, with transmission rates ranging from 4 to 21%, despite 85% antiretroviral therapy (ART) coverage among pregnant women. While ART...

Climate change and extreme weather events and linkages with HIV outcomes: Recent advances and ways forward

2025

PURPOSE OF REVIEW: Discuss the recent evidence on climate change and related extreme weather events (EWE) and linkages with HIV prevention and care outcomes. RECENT FINDINGS: We identified 22 studies...

Retention in care after transition to adult care for adolescents and young adults with HIV: A systematic review and meta-analysis

2025

Objective: To evaluate the retention rates of adolescents and young adults (aged 10-25 years) living with HIV during the transition to adult HIV care. Methods: The study involved 15 cohort studies conducted...

A scoping review: Forced/coerced sterilization as a socio-cultural risk factor for sexually transmitted HIV for older Black women

2025

Understanding socio-cultural factors that influence older (age 50 and up) Black women’s risk for sexually transmitted HIV has often been absent from policies and programs. This scoping review asked: What...

Prevalence of late HIV diagnosis and its impact on mortality: A comprehensive systematic review and meta-analysis

2025

Objectives: The late diagnosis of HIV infection plays a crucial role in accelerating the disease progression and increasing the risk of death in the HIV population. However, there remains no consensus...

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