SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Prevalence of HIV drug resistance among patients experiencing first-line treatment failure in Ethiopia: A systematic review and meta-analysis

2025

Background The emergence of human immunodefiency virus (HIV) drug resistance presents a substantial challenge. Alternatives for effective treatment regimens are limited, and treatment strategies are complicated. Although a number of...

Are Candida albicans isolates from people living with HIV more resistant to antifungals? A systematic review and meta-analysis

2025

People living with HIV (PLHIV) often require antifungal medications for the treatment or prevention of infections, which may contribute to the emergence of resistant Candida albicans strains. This systematic review...

Technologies for healthy lifestyle in people with HIV: A systematic review

2025

OBJECTIVE: to analyze clinical trials that assessed the effectiveness of technologies for healthy lifestyles in people with HIV. METHOD: A systematic review, conducted in five databases, with association of controlled...

Harms associated with injecting in public spaces: A global systematic review and meta-analysis

2025

BACKGROUND: Despite increasing backlash against harm reduction efforts and the need to understand the risk environments encountered by people who inject drugs (PWID), a quantitative systematic review on public injecting...

Prevalence of oral human papillomavirus infection in African countries: A systematic review and meta-analysis

2025

This meta-analysis aimed to provide pooled overall prevalence estimates of oral human papillomavirus (HPV) infection in Africa. A literature search for cross-sectional studies was conducted until January 2025. The Newcastle-Ottawa...

Measuring mobility in HIV research in sub-Saharan Africa: A scoping review

2025

INTRODUCTION: Mobility-from overnight travel to permanent migration-can reduce service access and increase HIV risk, driving the epidemic in sub-Saharan Africa (SSA). This scoping review described mobility measures used in HIV...

Association between antiretroviral therapy and dental caries in children and adolescents with HIV: A systematic review and meta-analysis

2025

OBJECTIVE: To evaluate the evidenceAÿregarding the association between antiretroviral therapy and dental caries in children and adolescents with HIV. METHODS: Searches were conducted in five international databases (PubMed, Scopus, EMBASE,...

Aetiology of fever of unknown origin in people living with HIV: A systematic review and meta-analysis

2025

Introduction: Fever of unknown origin (FUO) in people living with HIV presents a significant diagnostic challenge due to its broad range of potential aetiologies. Objective: The aims of this study were to...

The association between disclosure and antiretroviral therapy among adults living with HIV in China: A systematic review and meta-analysis

2025

Background Antiretroviral therapy (ART) and ART adherence are crucial for preventing HIV transmission and prolonging the lifespan of people living with HIV (PLWH). Serostatus disclosure is a significant factor influencing...

Comparison of treatment-emergent resistance-associated mutations and discontinuation due to adverse events among integrase strand transfer inhibitor-based single-tablet regimens and cabotegravir + rilpivirine for the treatment of virologically suppressed people with HIV: A systematic literature review and network meta-analysis

2025

Objective This study evaluated rates of treatment‐emergent resistance‐associated mutations (TE‐RAMs) and discontinuation due to adverse events (DC‐AEs) across integrase strand transfer inhibitor (INSTI)‐based single‐tablet regimens and injectable cabotegravir + rilpivirine...

The association between HIV infection and carotid intima-media thickness in the era of antiretroviral therapy: A meta-analysis

2025

Atherosclerosis remains a leading cause of mortality globally, and this is worse in people living with HIV (PLHIV). While the administration of antiretroviral therapy (ART) in this population has significant...

HIV, hepatitis, and syphilis self-testing among adolescents and young adults: A systematic review and meta-analysis

2025

Background: Adolescents and young adults (AYA) make up a significant share of the world’s burden of HIV and other sexually transmitted infections (STI). Self-testing can increase testing coverage and strengthen the...

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