SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Pulmonary function in people living with human immunodeficiency virus: A meta-analysis

2024

BACKGROUND: HIV can infect bronchial epithelial cells rendering individuals susceptible to lung damage. Our objective was to determine the effects of human immunodeficiency virus (HIV) infection on pulmonary function tests....

Prevalence of ocular toxoplasmosis among people living with HIV: A systematic review and meta-analysis

2024

Aim: To determine the prevalence of ocular toxoplasmosis among people living with HIV through a systematic review and meta-analysis. Materials & methods: A literature search was conducted, estimating pooled prevalence...

Systematic review and meta-analysis of the global prevalence of sexually transmitted infections in people living with HIV and associated risk factors

2023

People living with HIV (PLWH) constitute a vulnerable population for acquiring additional sexually transmitted infections (STIs). This study was conducted to provide a summary of the evidence on the global...

Effectiveness of statins in people living with HIV: A systematic review and meta-analysis of randomized controlled trials

2024

Introduction: People living with HIV (PLWH) receiving statin therapy have shown improved lipid profiles. However, they are not free from side effects, thereby requiring strict monitoring of the therapy. The meta-analysis...

Detection rates of mental health problems among sexual minorities in mainland China: A meta-analysis

2024

Previous studies that have addressed the growing mental health problems among sexual minorities in mainland China, but failed to inform mental health programs and public health policies with consistent detection...

Stigmatizing and inaccessible: The perspectives of female sex workers on barriers to reproductive healthcare utilization—A scoping review

2024

AIM: To systematically map the extent, range and nature of qualitative studies that explored female sex workers’ own perspectives on barriers to accessing reproductive healthcare services. DESIGN: A scoping review...

Incidence rate of mortality and its predictors among tuberculosis and human immunodeficiency virus coinfected patients on antiretroviral therapy in Ethiopia: Systematic review and meta-analysis

2024

Background Tuberculosis (TB) is the leading cause of death among HIV-infected adults and children globally. Therefore, this study was aimed at determining the pooled mortality rate and its predictors among...

Mortality and its predictors among human immunodeficiency virus-infected children younger than 15 years receiving antiretroviral therapy in Ethiopia: A systematic review and meta-analysis

2024

BACKGROUND: Despite antiretroviral treatment (ART), the human immunodeficiency virus (HIV) continues to pose a considerable health burden in resource-poor countries. This systematic review and meta-analysis aimed to determine the pooled...

Reactivation of Trypanosoma cruzi infection in immunosuppressed patients: A systematic review and meta-analysis

2024

Background: The risk of Trypanosoma cruzi reactivation is poorly understood. Previous studies evaluating the risk of reactivation report imprecise findings, and recommendations for monitoring and management from clinical guidelines rely...

Evaluating adverse reactions of central venous catheter placement in patients with AIDS: A meta-Analysis approach

2024

OBJECTIVE: This study aims to identify contributing factors to adverse reactions related to central venous catheter (CVC) usage in patients with HIV/AIDS, to enhance patient care and treatment outcomes. METHODS:...

Fast-track interventions for HIV and AIDS epidemic control among key populations: A rapid review

2024

BACKGROUND: Targeted interventions for key populations remain critical for realisation of epidemic control for human immunodeficiency virus (HIV) infection because of the causal relationship between HIV infection in the general...

Still far to go with characterisation of molecular and genetic features of diffuse large B-cell lymphoma in people living with HIV: A scoping review

2024

Diffuse large B-cell lymphoma (DLBCL) accounts for half of non-Hodgkin lymphoma cases in people living with human immunodeficiency syndrome (PLWH). The interplay of viremia, immune dysregulation and co-infection with oncogenic...

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