SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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The impact of place of residence on antiretroviral therapy adherence: A systematic review and meta-analysis

2025

Objective: There is evidence of geographical variation in HIV coverage and antiretroviral therapy (ART) adherence, and studies have investigated how the place of residence of people living with HIV (PLWH) influences...

Prevalence and predictors of virological failure among the people living with HIV on antiretroviral treatment in East Africa: Evidence from a systematic review with meta-analysis and meta-regression of published studies from 2016 to 2023

2025

Background: Virological failure (VF) significantly threatens the efficacy of antiretroviral therapy (ART) programs in East Africa. This systematic review and meta-analysis assess the prevalence and predictors of VF among individuals living...

Risk factors and mortality outcomes of COVID-19 in people living with HIV: A systematic review and meta-analysis

2024

This study was performed to reveal the risk factors associated with mortality in people living with HIV (PLHIV) who were diagnosed with COVID-19. Studies reporting deaths among PLHIV and infected...

Chronic kidney disease among people living with HIV on TDF based regimen: A systematic review and meta-analysis

2025

INTRODUCTION: Chronic kidney disease is a major public health concern among people living with human immunodeficiency virus (PLWHIV) who are taking tenofovir disoproxil fumarate-based regimen. Despite the available evidence showing...

A review of network models for HIV spread

2025

BACKGROUND: HIV/AIDS has been a global health crisis for over 4 decades. Network models, which simulate human behavior and intervention impacts, have become an essential tool in guiding HIV prevention...

Viral load suppression rate of third-line antiretroviral therapy and its association with gender among HIV patients after second-line treatment failure in Africa: A systematic review and meta-analysis

2025

INTRODUCTION: Previous works of literatures on the viral load suppression rate of third line antiretroviral therapy in Africa has produced inconsistent and inconclusive results, with rates varying between 62% and...

Global epidemiology of HIV among dialysis patients: A systematic review and meta-analysis

2025

HIV transmission and infection among dialysis patients have become a major healthcare concern and a rising threat throughout the world. Our current systematic review and meta-analysis targeted to determine the...

Prevalence of human papillomavirus and genotype distribution in Chinese men: A systematic review and meta-analysis

2025

BACKGROUND: Human papillomavirus (HPV) vaccination represents a cost-effective strategy for preventing HPV-related diseases across genders. However, the HPV vaccine has not been approved for mainland Chinese males, and the comprehensive...

The impact of HPV/HIV co-infection on immunosuppression, HPV genotype, and cervical cancer biomarkers

2025

BACKGROUND: Human papillomavirus (HPV) and human immunodeficiency virus (HIV) co-infection present a significant impact on women’s health globally, especially in immunocompromised individuals. HIV-induced immunosuppression promotes the persistence of high-risk HPV...

Multidrug resistance tuberculosis in the context of co-infection in Ethiopia: A systematic review and meta-analysis

2025

The rise of multidrug-resistant tuberculosis (MDR-TB) remains a critical public health challenge, particularly in developing countries like Ethiopia. This systematic review and meta-analysis aimed to estimate the pooled prevalence of...

Leveraging U=U in interventions for Black women living with HIV: A scoping review and call to action

2025

Despite significant reductions in the incidence and prevalence of human immunodeficiency virus (HIV) over recent decades, certain subgroups continue to experience disproportionate HIV-related health disparities. Cisgender Black women, in particular,...

Success rates of endodontic treatment in HIV positive (HIV +) and non-HIV patients—A systematic review

2025

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