SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Understanding HIV-exposed uninfected children: A narrative review

2025

The widespread implementation of antiretroviral therapy has significantly reduced HIV-related mortality and mother-to-child transmission. Despite being HIV-uninfected, HIV-exposed children (HEU) seem to face heightened risks of immune dysfunction, cardiometabolic diseases,...

Prevalence of late HIV diagnosis and its impact on mortality: A comprehensive systematic review and meta-analysis

2025

Objectives: The late diagnosis of HIV infection plays a crucial role in accelerating the disease progression and increasing the risk of death in the HIV population. However, there remains no consensus...

Growth of children who are HIV-exposed but uninfected: A systematic review and meta-analysis

2025

BACKGROUND: Pooled analyses summarising long-term growth outcomes in children who are HIV-exposed uninfected (HEU) compared with children who are HIV-unexposed (HU) are lacking. We aimed to summarise the existing literature...

Prevalence of human papillomavirus and genotype distribution in Chinese men: A systematic review and meta-analysis

2025

BACKGROUND: Human papillomavirus (HPV) vaccination represents a cost-effective strategy for preventing HPV-related diseases across genders. However, the HPV vaccine has not been approved for mainland Chinese males, and the comprehensive...

HIV-1 resistance and virological failure to treatment with the integrase inhibitors bictegravir, cabotegravir, and dolutegravir: A systematic literature review

2024

We describe and analyze resistance-associated mutations (RM) and virological failures (VF) on antiretroviral therapy using the latest approved integrase inhibitors (INIs) dolutegravir (DTG), bictegravir (BIC), and cabotegravir (CAB), together with...

The impact of HPV/HIV co-infection on immunosuppression, HPV genotype, and cervical cancer biomarkers

2025

BACKGROUND: Human papillomavirus (HPV) and human immunodeficiency virus (HIV) co-infection present a significant impact on women’s health globally, especially in immunocompromised individuals. HIV-induced immunosuppression promotes the persistence of high-risk HPV...

A systematic review and meta-analysis of HIV/AIDS prevalence among transgender populations worldwide

2025

BACKGROUND AND AIMS: The study’s goal was to assess the global prevalence of HIV/AIDS infection in transgender people and to provide light on regional variances. METHODS: A systematic search was...

Success rates of endodontic treatment in HIV positive (HIV +) and non-HIV patients—A systematic review

2025

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HIV infection and esophageal cancer in sub-Saharan Africa: A comprehensive meta-analysis

2024

Africa hosts the highest burden of esophageal cancer (49%) and HIV (60%) worldwide. It is imperative to investigate the synergistic impact of these two diseases on African populations. This study...

Voluntary HIV testing and counselling initiatives in occupational settings: A scoping review

2025

Voluntary HIV testing and counselling (VCT) in the workplace could reach population groups who may be at risk for HIV but may not readily seek out testing from other services....

Risk factors and mortality outcomes of COVID-19 in people living with HIV: A systematic review and meta-analysis

2024

This study was performed to reveal the risk factors associated with mortality in people living with HIV (PLHIV) who were diagnosed with COVID-19. Studies reporting deaths among PLHIV and infected...

HIV and the gut microbiome: Future research hotspots and trends

2025

BACKGROUND: The use of highly active antiretroviral therapy has transformed AIDS into a chronic infectious disease, but issues of chronic inflammation and immune system activation persist. Modulating the gut microbiome...

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