SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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The impact of HIV coinfection on Mpox patients: A systematic review and meta-analysis

2026

A substantial proportion of mpox cases occur in people with HIV, but how HIV coinfection and immune status affect clinical outcomes remains unclear. We systematically searched major databases up to...

Burden and clinical impact of ‘neglected’ transfusion-transmitted infections in Cameroon: A systematic review and meta-analysis

2026

Background Blood supply is a public health challenge in African countries. In Cameroon, blood selection guidelines focus on four viral and bacterial pathogens (HIV, hepatitis B and C viruses, Treponema pallidum)...

Prevalence and risk of cardiovascular events among people living with HIV: A meta-analysis

2026

BACKGROUND: People living with HIV (PLWH) have increased cardiovascular risk, but the contribution of HIV-related factors to all-cause cardiovascular events remains unclear. We assessed the prevalence and determinants of cardiovascular...

Organization and integration of care in the HIV-non-communicable disease syndemic: A rapid scoping review

2026

Advances in antiretroviral therapy have transformed infection with HIV into a manageable chronic disease, increasing the survival of people living with HIV, who are also undergoing a demographic aging process...

Global mental health disparities among transgender women and transfeminine people living with HIV: A systematic review and meta-analysis of 63 studies

2026

Background Transgender women and transfeminine people face a disproportionate burden of mental health conditions driven by stigma, discrimination, and structural inequities, with additional psychosocial challenges related to HIV diagnosis and...

Barriers and facilitators to healthcare access among Sub-Saharan African migrants in Europe: A scoping review

2026

Background Sub-Saharan African (SSA) migrants represent a significant and growing proportion of Europe’s diverse migrant population; yet face substantial barriers in accessing healthcare services. Understanding these barriers is essential for...

Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications

2026

Dolutegravir underpins modern first- and second-line HIV treatment regimens; however, interindividual variability in its disposition and tolerability presents challenges for optimal use. This scoping review mapped current evidence on the...

Detectability of pathogenic RNA virus families in different body sites: A scoping review

2026

Nucleic acid amplification tests (NAATs) are central to modern virology diagnostics. However, evidence supporting alternative specimen types remains uneven across viral families, especially for emerging viruses. This limits diagnostic flexibility...

Healthcare access in chemsex contexts in Brazil: A scoping review and the VIP-chemsex model

2026

Background/Objectives: Sexualized drug use (SDU) and chemsex have emerged as a growing public health concern globally, reflecting complex intersections between sexual practices, psychoactive substance use, and structural vulnerabilities. In Brazil, however,...

Prevalence of HIV and hepatitis B co-infection in Nigeria: A systematic review and meta-analysis

2026

Introduction Hepatitis B virus (HBV) and Human Immunodeficiency virus (HIV) infections are both major public health concerns in sub-Saharan Africa. Co-infection with these virus accelerates liver disease progression, increases hepatotoxicity,...

The impact of APOE ε4 on cognitive performance in adults with HIV: A systematic review and meta-analysis

2026

Objective: With a rapidly aging population living with HIV that may face a double-hit of neuroHIV and Alzheimer’s disease, the objective of this meta-analysis was to evaluate the impact of...

Incidence of occupational HIV seroconversion among healthcare workers: A systematic review and meta-analysis

2026

Background Healthcare workers (HCWs) may be at elevated risk of HIV infection due to the global HIV burden and frequent occupational exposure to blood and body fluids (BBF). This systematic...

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