SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Performance of point-of-care CD4 testing technologies in resource-constrained settings: A systematic review and meta-analysis

2016

BACKGROUND: Point-of-care (POC) CD4 testing increases patient accessibility to assessment of antiretroviral therapy eligibility. This review evaluates field performance in low and middle-income countries (LMICs) of currently available POC CD4...

Accuracy of the interferon-gamma release assay for the diagnosis of active tuberculosis among HIV-seropositive individuals: A systematic review and meta-analysis

2016

BACKGROUND: Although the interferon-gamma release assay (IGRA) has become a widely accepted means for the diagnosis of latent tuberculosis infection (LTBI), the role of the IGRA in diagnosing active tuberculosis...

Registry-based outcome assessment in haemophilia: A scoping study to explore the available evidence

2016

Haemophilia is a congenital disorder with bleeding episodes as its primary symptom. These episodes can result in negative outcomes including joint damage, loss of active days due to hospitalization and...

Risk of colorectal cancer and associated mortality in HIV: A systematic review and meta-analysis

2017

BACKGROUND: As people with HIV live longer, the numbers of colorectal cancer cases are expected to increase. We sought to compare the colorectal cancer incidence and cause-specific mortality among people...

Status and methodology of publicly available national HIV care continua and 90-90-90 targets: A systematic review

2017

BACKGROUND: In 2014, the Joint United Nations Program on HIV/AIDS (UNAIDS) issued treatment goals for human immunodeficiency virus (HIV). The 90-90-90 target specifies that by 2020, 90% of individuals living...

Oral direct-acting agent therapy for hepatitis C virus infection: A systematic review

2017

Background: Rapid improvements in hepatitis C virus (HCV) therapy have led to the approval of multiple oral direct-acting antiviral (DAA) regimens by the U.S. Food and Drug Administration (FDA) for...

Methods used and topics addressed in quantitative health research on gay, bisexual and other men who have sex with men: A systematic review of the literature

2017

Research on sexual minority men (gay, bisexual, and other men who have sex with men) was examined with regard to the measures of sexual orientation used, the methods of research,...

Examining the health and health service utilization of heterosexual men with HIV: A community-informed scoping review

2017

The prevalence of HIV infection among heterosexual men has increased. Consequently, the need for health and support services for this group is likely to increase. We conducted a scoping review...

Are religion and spirituality barriers or facilitators to treatment for HIV: A systematic review of the literature

2017

Much attention has been given to the relationship between religion/spirituality (R/S) and HIV in recent years, but comparatively little has been explored in regard to R/S and HIV testing, retention...

Initiation and completion rates for latent tuberculosis infection treatment: A systematic review

2016

BACKGROUND: Control of latent tuberculosis infection (LTBI) is an important step towards tuberculosis elimination. Preventive treatment will prevent the development of disease in most cases diagnosed with LTBI. However, low...

How to assess gay, bisexual and other men who have sex with men for chemsex

2016

OBJECTIVES: Sexualised substance use, ‘chemsex’, is being increasingly reported by gay, bisexual and other men who have sex with men (GBMSM) in sexual health clinics. We aim to describe the...

Critical review: What dose of rifabutin is recommended with antiretroviral therapy?

2016

Since the advent of combination antiretroviral therapy to successfully treat HIV infection, drug-drug interactions (DDIs) have become a significant problem as many antiretrovirals (ARVs) are metabolized in the liver. Antituberculous...

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