SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Peripheral immune dysregulation in the ART era of HIV-associated neurocognitive impairments: A systematic review

2020

Human immunodeficiency virus-associated neurocognitive impairment (HANI) remains problematic despite the effective use of antiretroviral therapy (ART) and viral suppression. A dysregulated immune response contributes to the development of HANI but...

Factors associated with HIV testing among people who inject drugs: A meta-analysis

2020

HIV testing is the first step to early identification, treatment and management of HIV infection among people involved in high-risk behaviors specifically drug injection. Achieving declines in morbidity and mortality...

What is the most appropriate induction regimen for the treatment of HIV-associated Cryptococcal meningitis when the recommended regimen is not available? Evidence from a network meta-analysis

2020

Aims: Our object was to find the most appropriate, most effective, and most readily available of four induction regimens for HIV-associated cryptococcal meningitis (CM) (Regimen A: 1 week of AmB...

A systematic review and meta-analyses on initiation, adherence and outcomes of antiretroviral therapy in incarcerated people

2020

BACKGROUND: Incarcerated people are at increased risk of human immunodeficiency virus (HIV) infection relative to the general population. Despite a high burden of infection, HIV care use among prison populations...

Factors associated with injecting-related risk behaviors among people who inject drugs: A systematic review and meta-analysis study

2020

We conducted this systematic review and meta-analysis study to better understand the factors (being drug use, drug type (methamphetamine vs others), sex partner, frequency of injection, homelessness and being HIV...

Global burden of hypertension among people living with HIV in the era of increased life expectancy: A systematic review and meta-analysis

2020

BACKGROUND: Although HIV infection and antiretroviral therapy (ART) increase the risk for hypertension in people living with HIV (PLHIV), the global and regional burden of hypertension in PLHIV is not...

Clinician barriers and facilitators to routine HIV testing: A systematic review of the literature

2020

BACKGROUND: Routine HIV screening rates are suboptimal. OBJECTIVES: This systematic review identified barriers to/facilitators of routine HIV testing, categorized them using the socioecological model (SEM), and provided recommendations for interventions...

Oral pre-exposure prophylaxis (PrEP) continuation, measurement, and reporting: A systematic review and meta-analysis

2020

OBJECTIVE: To appropriately plan for rollout and monitor impact of oral pre-exposure prophylaxis (PrEP) it is important to understand PrEP continuation and come to a consensus on how best to...

A systematic review of recent methodological approaches for using ecological momentary assessment to examine outcomes in U.S. based HIV research

2020

PURPOSE OF REVIEW: In recent years, researchers have been adopting and using ecological momentary assessment (EMA) methods via technology devices for real-time measurement of exposures and outcomes in HIV research....

Bone fracture among people living with HIV: A systematic review and meta-regression of prevalence, incidence, and risk factors

2020

INTRODUCTION: People living with HIV (PLWH) had a higher prevalence and incidence rate of bone fracture compared to general population. Although several studies have explored this phenomenon, the prevalence and...

HIV, antiretroviral therapy and metabolic alterations: A review

2020

The introduction of antiretroviral therapy (ART) has caused some metabolic problems to people who suffer from HIV. ART probably is not the sole reason for these metabolic disorders. Most likely,...

A review of usability evaluation methods and their use for testing eHealth HIV interventions

2020

PURPOSE OF REVIEW: To provide a comprehensive review of usability testing of eHealth interventions for HIV. RECENT FINDINGS: We identified 28 articles that assessed the usability of eHealth interventions for...

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