SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Immune checkpoint inhibitor therapy for cancer patients infected with HIV: A systematic review

2020

BACKGROUND: Immune checkpoint inhibitor (ICI) therapy represents a breakthrough in cancer treatment. However, clinical trials of ICI have usually excluded people living with HIV (PLWH). The efficacy and safety data...

impact of pre-antiretroviral therapy CD4 counts on drug resistance and treatment failure: A systematic review

2020

The continuous rising of HIV drug resistance in low- and middle-income countries and its impact on treatment failure is a growing threat for the HIV treatment response. This review aimed...

A systematic review and meta-analyses on initiation, adherence and outcomes of antiretroviral therapy in incarcerated people

2020

BACKGROUND: Incarcerated people are at increased risk of human immunodeficiency virus (HIV) infection relative to the general population. Despite a high burden of infection, HIV care use among prison populations...

A systematic review of technology-assisted HIV testing interventions

2020

PURPOSE OF REVIEW: The purpose of this review is to describe and assess the literature on mobile health (mHealth) and other technology-based HIV testing interventions published in the 5-year period...

A realist systematic review of stigma reduction interventions for HIV prevention and care continuum outcomes among men who have sex with men

2020

While stigma associated with human immunodeficiency virus (HIV) infection among men who have sex with men (MSM) is well recognized, there remains relatively limited intervention data on effective stigma reduction...

Impact of male circumcision on risk of HIV infection in men in a changing epidemic context — Systematic review and meta-analysis

2020

INTRODUCTION: WHO/UNAIDS recommended Voluntary Medical Male Circumcision in 2007 based on systematic review of observational studies prior to 1999 and three randomized controlled trials (RCTs). To inform updated WHO guidance,...

A review of HIV pre-exposure prophylaxis (PrEP) programmes by delivery models in the Asia-Pacific through the healthcare accessibility framework

2020

INTRODUCTION: In the Asia-Pacific, pre-exposure prophylaxis (PrEP) is a newly introduced public health intervention for minimizing HIV transmission, the coverage of which has remained limited. The best delivery models and...

Socio-demographic characteristics and risk factors for HIV transmission in female bar workers in sub-Saharan Africa: A systematic literature review

2020

BACKGROUND: Although sex workers are considered a key population in the HIV epidemic in sub-Saharan Africa (SSA), less consideration has been given to female bar workers (FBW), whose primary occupation...

What is the most appropriate induction regimen for the treatment of HIV-associated Cryptococcal meningitis when the recommended regimen is not available? Evidence from a network meta-analysis

2020

Aims: Our object was to find the most appropriate, most effective, and most readily available of four induction regimens for HIV-associated cryptococcal meningitis (CM) (Regimen A: 1 week of AmB...

Effect of omega-3 polyunsaturated fatty acids treatment on lipid pattern of HIV patients: A meta-analysis of randomized clinical trials

2020

Even though omega-3 polyunsaturated fatty acids (PUFAs) seem to be effective in the treatment of human immunodeficiency virus (HIV)-associated dyslipidemia, their impact is still debated. For this reason, our aim...

Oral pre-exposure prophylaxis (PrEP) continuation, measurement, and reporting: A systematic review and meta-analysis

2020

OBJECTIVE: To appropriately plan for rollout and monitor impact of oral pre-exposure prophylaxis (PrEP) it is important to understand PrEP continuation and come to a consensus on how best to...

A systematic review of recent methodological approaches for using ecological momentary assessment to examine outcomes in U.S. based HIV research

2020

PURPOSE OF REVIEW: In recent years, researchers have been adopting and using ecological momentary assessment (EMA) methods via technology devices for real-time measurement of exposures and outcomes in HIV research....

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