SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Improving engagement in the HIV care cascade: A systematic review of interventions involving people living with HIV/AIDS as peers

2016

Improving patient engagement in HIV care is critical for maximizing the impact of antiretroviral therapy (ART). We conducted a systematic review of studies that used HIV-positive peers to bolster linkage,...

Reversing gut damage in HIV infection: Using non-human primate models to instruct clinical research

2016

Antiretroviral therapy (ART) has led to dramatic improvements in the lives of HIV-infected persons. However, residual immune activation, which persists despite ART, is associated with increased risk of non-AIDS morbidities....

Adjunctive corticosteroids for the treatment of pneumonia in patients with HIV: A meta-analysis

2016

The present study aimed to evaluate the effects of adjunctive corticosteroid treatment on Pneumocystis jiroveci pneumonia in patients with human immunodeficiency virus (HIV). A literature search of relevant randomized controlled...

Dynamic transmission economic evaluation of infectious disease interventions in low- and middle-income countries: A systematic literature review

2016

Economic evaluation using dynamic transmission models is important for capturing the indirect effects of infectious disease interventions. We examine the use of these methods in low- and middle-income countries, where...

Adverse events associated with abacavir use in HIV-infected children and adolescents: A systematic review and meta-analysis

2015

BACKGROUND: Concerns exist about the toxicity of drugs used in the implementation of large-scale antiretroviral programmes, and documentation of antiretroviral toxicity is essential. We did a systematic review and meta-analysis...

Cerebral aneurysms associated with human immunodeficiency virus in adults: Literature review and new perspectives

2016

INTRODUCTION: the treatment of human immunodeficiency virus (HIV) infection has been decreasing patient morbidity and mortality by opportunistic infections and, thus, survival has increased. This new reality has been changing...

Partner services in sexually transmitted disease prevention programs: A review

2016

BACKGROUND: Partner services have been a mainstay of public health sexually transmitted disease (STD) prevention programs for decades. The principal goals are to interrupt transmission and reduce STD morbidity and...

A synthesis of meta-analytic evidence of behavioral interventions to reduce HIV/STIs

2016

To identify the mode of delivery, communicator, and content dimensions that make STI/HIV prevention interventions most successful at increasing condom use/protected sex or reducing STI/HIV incidence. A literature search for...

Prevalence of hepatitis C virus infection among HIV+ men who have sex with men: A systematic review and meta-analysis

2016

Since 2000, an increase in hepatitis C virus infection among HIV-infected (HIV+) men who have sex with men has been observed. Evidence points to blood exposure during sex as the...

HIV and sexual risk among men who have sex with men and women in Asia: A systematic review and meta-analysis

2016

We performed a systematic review to estimate the proportion of men who have sex with men (MSM) in Asia who are bisexual and compare prevalence of HIV and sexual risk...

The views and experiences of nurses and midwives in the provision and management of provider-initiated HIV testing and counseling: A systematic review of qualitative evidence

2016

BACKGROUND: Global progress towards HIV prevention and care is contingent upon increasing the number of those aware of their status through HIV testing. Provider-initiated HIV testing and counseling is recommended...

Systematic review to determine the prevalence of transmitted drug resistance mutations to rilpivirine in HIV-infected treatment-naive persons

2016

BACKGROUND: Transmitted drug resistance to antiretrovirals in HIV-1 infected individuals is rising in some regions, and could compromise the effectiveness of first-line treatment. It is important to understand the prevalence...

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