SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Factors associated with injecting-related risk behaviors among people who inject drugs: A systematic review and meta-analysis study

2020

We conducted this systematic review and meta-analysis study to better understand the factors (being drug use, drug type (methamphetamine vs others), sex partner, frequency of injection, homelessness and being HIV...

The effectiveness of electronic health interventions for promoting HIV-preventive behaviors among men who have sex with men: Meta-analysis based on an integrative framework of design and implementation features

2020

BACKGROUND: The disproportionately high prevalence of HIV among men who have sex with men (MSM) is a global concern. Despite the increasing utilization of electronic health (eHealth) technology in the...

Social and structural determinants of household support for art adherence in low- and middle-income countries: A systematic review

2020

Adherence to HIV antiretroviral therapy (ART) is a crucial factor in health outcomes for people living with HIV (PLWH). Interventions to support ART adherence are increasingly focused on the household...

Peripheral immune dysregulation in the ART era of HIV-associated neurocognitive impairments: A systematic review

2020

Human immunodeficiency virus-associated neurocognitive impairment (HANI) remains problematic despite the effective use of antiretroviral therapy (ART) and viral suppression. A dysregulated immune response contributes to the development of HANI but...

Injecting risk behaviours amongst people who inject drugs: A global multi-stage systematic review and meta-analysis

2020

BACKGROUND: Injecting risk behaviour, such as receptive sharing of injecting equipment and/or re-using one’s equipment, is associated with bloodborne virus transmission and infections in people who inject drugs (PWID). We...

mHealth and opportunities in anti-retroviral adherence in HIV, a diverse group of patients with diverse and unique opportunities: A narrative review

2020

BACKGROUND: Antiretrovirals (ARVs) are key in the management of human immunodeficiency virus (HIV). While no cure exists, ARVs help patients live healthy lives and prevent transmission to others. However, adherence...

Cryptococcal meningitis: A review of cryptococcal antigen screening programs in Africa

2020

INTRODUCTION: Cryptococcal meningitis remains a significant contributor to AIDS-related mortality despite widened access to antiretroviral therapy. Cryptococcal antigen (CrAg) can be detected in the blood prior to development of meningitis....

Effect of omega-3 polyunsaturated fatty acids treatment on lipid pattern of HIV patients: A meta-analysis of randomized clinical trials

2020

Even though omega-3 polyunsaturated fatty acids (PUFAs) seem to be effective in the treatment of human immunodeficiency virus (HIV)-associated dyslipidemia, their impact is still debated. For this reason, our aim...

Factors associated with HIV testing among people who inject drugs: A meta-analysis

2020

HIV testing is the first step to early identification, treatment and management of HIV infection among people involved in high-risk behaviors specifically drug injection. Achieving declines in morbidity and mortality...

Impact of mobile phone-based interventions on methamphetamine use and high-risk sexual behaviors in men who have sex with men (MSM): A systematic review

2020

Background: Today, increased use of methamphetamine in homosexual men is associated with high-risk sexual behaviors and (HIV) epidemic. Mobile phone-based interventions are an accessible and rapid method to provide healthcare...

Use of the multiplier method to estimate the size of populations most at risk of human immunodeficiency virus infection in China: A systematic review

2020

OBJECTIVE: United Nations Programme on human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome and World Health Organization believe that some of the benchmark numbers collected may be inaccurate when using the multiplier...

Direct-acting antivirals for HCV treatment in older patients: A systematic review and meta-analysis

2020

The advent of highly effective and well-tolerated direct antiviral antivirals (DAAs) has dramatically changed the landscape of chronic hepatitis C. The effect of DAAs in older adults is difficult to...

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