SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Stigma reduction interventions in people living with HIV to improve health-related quality of life

2020

As the UNAIDS 90-90-90 targets for people living with HIV are increasingly being reached in many contexts, health-related quality of life, the so-called fourth 90, warrants special attention. HIV-related stigma...

Effects of psychosocial interventions on children affected by parental HIV/AIDS: A meta-analysis on depression and anxiety

2019

BACKGROUND: Children orphaned by parental AIDS or those of parents with HIV infection demonstrate many negative mental health outcomes. Different types of psychosocial interventions have been conducted to improve the...

The prevalence of HIV among MSM in China: A large-scale systematic analysis

2019

BACKGROUND: The prevalence of HIV among men who have sex with men (MSM) has become a significant public health challenge. The aim was to comprehensively estimate the national prevalence of...

Cost of differentiated HIV antiretroviral therapy delivery strategies in sub-Saharan Africa: A systematic review

2019

BACKGROUND: Efficient and scalable models for HIV treatment are needed to maximize health outcomes with available resources. By adapting services to client needs, differentiated antiretroviral therapy (DART) has the potential...

Crowdsourcing methods to enhance HIV and sexual health services: A scoping review and qualitative synthesis

2019

BACKGROUND: Crowdsourcing is increasingly used to improve community engagement in HIV and sexual health research. In this scoping review, we reviewed studies using crowdsourcing approaches in HIV and sexual health...

Attrition of HIV-positive children from HIV services in low and middle-income countries

2019

INTRODUCTION: Identification and retention of HIV-positive children in HIV services is essential to ensure optimal health outcomes. This systematic review and meta-analysis examines the magnitude of attrition [loss to follow-up...

MicroRNAs and exosomes: Key players in HIV pathogenesis

2019

OBJECTIVES: HIV infection is well known to cause impairment of the human immune system, and until recently was a leading cause of death. It has been shown that T lymphocytes...

Factors associated with general sexual functioning and sexual satisfaction among people living with HIV: A systematic review

2019

Sexual difficulties, experienced by half of the people living with HIV (PLWH), not only affect quality of life but have been associated with lower adherence to antiretroviral medication. This systematic...

Comparison of different human papillomavirus (HPV) vaccine types and dose schedules for prevention of HPV-related disease in females and males

2019

BACKGROUND: Uptake of human papillomavirus (HPV) vaccine remains low in many countries, although the bivalent and quadrivalent HPV vaccines given as a three-dose schedule are effective in the prevention of...

HBV infection in HIV-driven immune suppression

2019

Worldwide, approximately 10% of all human immunodeficiency virus (HIV)-infected people are also chronically coinfected with hepatitis B virus (HBV). HBV infection has a poor prognosis in HIV-positive people and has...

Analysis of systematic reviews of medication adherence interventions for persons with HIV, 1996–2017

2019

This overview of reviews summarizes the evidence from systematic reviews (SR) on the effectiveness of antiretroviral therapy (ART) adherence interventions for people with HIV (PWH) and descriptively compares adherence interventions...

Brain structure of perinatally HIV-infected patients on long-term treatment: A systematic review

2019

Objective: We aim to give an overview of the available evidence on brain structure and function in PHIV-infected patients (PHIV+) using long-term combination antiretroviral therapy (cART) and how differences change...

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