SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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HIV-1, HAART and cancer: A complex relationship

2019

HIV infected people are at higher risk of developing cancer, although it is globally diminished in the era of highly active antiretroviral treatment (HAART). Recently, antioncogenic properties of some HAART...

The association of memory disorders and chronic HIV disease in the antiretroviral therapy era: A systematic literature review

2019

OBJECTIVES: Despite recent pharmacological progress, memory impairment is still frequently reported in people living with HIV. We aimed to conduct a systematic literature review investigating the presence of impairment of...

Peer-led self-management Interventions and adherence to antiretroviral therapy among people living with HIV: A systematic review

2019

Adherence to antiretroviral therapy (ART) is essential to reduce morbidity and mortality among people living with HIV (PLWH). However, adherence remains suboptimal, and PLWH may benefit from more self-management support...

Barriers to the use of mobile health in improving health outcomes in developing countries: Systematic review

2019

BACKGROUND: The use of mobile health (mHealth) technologies to improve population-level health outcomes around the world has surged in the last decade. Research supports the use of mHealth apps to...

Definition of immunological non-response to antiretroviral therapy: A systematic review

2019

BACKGROUND: Terms and criteria to classify people living with HIV on antiretroviral therapy (ART) who fail to achieve satisfactory CD4 T cell counts are heterogeneous, and need revision and summarization....

Difference in Toxoplasma gondii seroprevalence rates due to low and high CD4 counts in patients with HIV/AIDS

2019

Objective: Since symptomatic toxoplasmosis in in human immunodeficiency virus (HIV)/Acquired immunodeficiency syndrome (AIDS) almost always occurs as a result of reactivation of chronic infection, screening Toxoplasma serology has an important...

Technology-delivered psychotherapeutic interventions in improving depressive symptoms among people with HIV/AIDS: A systematic review and meta-analysis of randomised controlled trials

2019

With the increasing popularity of advanced technology, technology-delivered psychotherapeutic interventions (TPIs) may play a promising role in improving depressive symptoms among PLWHA. However, its effectiveness remains unclear. We aimed to...

Immunological efficacy of Tenofovir disproxil fumarate-containing regimens in Patients With HIV-HBV coinfection: A systematic review and meta-analysis

2019

Background: Hepatitis B virus (HBV) coinfection is common in HIV-positive patients. HIV infection modifies the natural course of HBV infection, leading to a faster progression of liver-related morbidity and mortality...

Abnormal QTc syndrome in HIV-infected patients: A systematic review of prevalence and risk factors

2019

BACKGROUND: The purpose of this review is to critically analyze data regarding the prevalence and risk factors for developing a prolonged QTc interval and subsequent sudden cardiac death (SCD) in...

Risk factors for infectious diseases in urban environments of sub-Saharan Africa: A systematic review and critical appraisal of evidence

2019

Our world is rapidly urbanizing. According to the United Nations, between 1990 and 2015, the percent of the world’s population living in urban areas grew from 43% to 54%. Estimates...

Adjuvanted-influenza vaccination in patients infected with HIV: A systematic review and meta-analysis of immunogenicity and safety

2019

Adjuvanted-influenza vaccination is an efficient method for enhancing the immunogenicity of influenza split-virus vaccines for preventing influenza. However, the medical community’s understanding of its performance in patients infected with HIV...

The effects of decentralising antiretroviral therapy care delivery on health outcomes for adolescents and young adults in low- and middle-income countries: A systematic review

2019

Background: Decentralisation of antiretroviral therapy has been implemented to scale up HIV care provision for patients in resource-limited countries. Youth living with HIV demonstrate the poorest care outcomes, compared to...

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