SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Antiretroviral therapy-associated metabolic complications: Review of the recent studies

2020

The extensive utilization of antiretroviral therapy (ART) has successfully improved human immunodeficiency virus (HIV)-associated complications. The incidence of opportunistic infections is decreased by the viral load suppression and the CD4...

The relationship between potentially traumatic or stressful events, HIV infection and neurocognitive impairment (NCI): A systematic review of observational epidemiological studies

2020

BACKGROUND: HIV/AIDS and potentially traumatic events (PTEs) or stressful life events (SLEs) and/or PTSD are independently associated with neurocognitive impairment (NCI). Literature suggests that HIV and PTE/SLE exposure independently and...

Integrating intra-individual and dyadic factors in examining health among gay and bisexual men: A narrative review of recent literature

2020

Gay and bisexual men (GBM) experience disproportionate rates of mental health and other negative health outcomes. For GBM in relationships, contextualizing the myriad of negative outcomes as a dyadic process...

Hepatitis E seroprevalence and viremia rate in immunocompromised patients: A systematic review and meta-analysis

2020

BACKGROUND AND AIMS: Hepatitis E is an infectious disease of the liver caused by the hepatitis E virus (HEV). Immunocompromised patients present a particular risk group, as chronification of hepatitis...

Efficacy of HIV interventions in African fishing communities: A systematic review and qualitative synthesis

2020

OBJECTIVES: This systematic review aims to qualitatively synthesise existing evidence on the efficacy of HIV interventions in African fishing communities. METHODS: Five databases (NCBI PubMed, EMBASE, Web of Science Core...

Utility of short message service (SMS) for remote data collection for HIV in low- and middle-income countries

2020

PURPOSE OF REVIEW: Short message system (SMS) communication is widespread in low- and middle-income countries (LMICs), and may be a viable approach to address challenges with in-person data collection for...

Implications of COVID-19 in high burden countries for HIV/TB: A systematic review of evidence

2020

BACKGROUND: The triple burden of COVID-19, tuberculosis and human immunodeficiency virus is one of the major global health challenges of the twenty-first century. In high burden HIV/TB countries, the spread...

Risk of failure in dual therapy versus triple therapy in naive HIV-patients: A systematic review and meta-analysis

2020

BACKGROUND: Several attempts have been made to test different drug-sparing strategies to reduce the drug-burden and drug-related toxicities. OBJECTIVE: The objective of this meta-analysis was to evaluate the relative risk...

Acute and early HIV infection screening among men who have sex with men, a systematic review and meta-analysis

2020

INTRODUCTION: Screening for acute and early HIV infections (AEHI) among men who have sex with men (MSM) remains uncommon in sub-Saharan Africa (SSA). Yet, undiagnosed AEHI among MSM and subsequent...

Community-based psychosocial substance use disorder interventions in low-and-middle-income countries: A narrative literature review

2020

BACKGROUND: Mental health and substance use disorders (SUDs) are the world’s leading cause of years lived with disability; in low-and-middle income countries (LIMCs), the treatment gap for SUDs is at...

Nature of, and responses to key sexual and reproductive health challenges for adolescents in urban slums in sub-Saharan Africa: A scoping review

2020

BACKGROUND: Addressing adolescents’ sexual and reproductive health and rights (SRHR) requires an understanding of the socio-cultural and spatial settings within which they live. One setting of particular importance is the...

Improving male involvement in antenatal care in low and middle-income countries to prevent mother to child transmission of HIV: A realist review

2020

BACKGROUND: Childhood Human Immunodeficiency Virus (HIV) infection occurs almost exclusively via mother to child transmission (MTCT) during pregnancy, birth, or through breastfeeding. Recent studies have shown that male involvement (MI)...

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