SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Effects of exercise modality and intensity on the CD4 count in people with HIV: A systematic review and meta-analysis

2021

The purpose of this study was to assess the effect of training modality and exercise intensity on the modulation of lymphocytes CD4 count in people living with HIV (PLWH). A...

Knowledge, attitude and practice of cervical cancer screening among women infected with HIV in Africa: Systematic review and meta-analysis

2021

BACKGROUND: To establish successful strategies and increasing the utilization of preventive services, there is a need to explore the extent to which the general female population is aware and use...

COVID-19 in people living with HIV: A systematic review and meta-analysis

2021

COVID-19 is a global health emergency. People living with human immunodeficiency virus (PLHIV) have concerns about whether they have a higher risk of getting the infection and suffer worse COVID-19...

Predictors of lost to follow up from antiretroviral therapy among adults in sub-Saharan Africa: A systematic review and meta-analysis

2021

Background: It is known that ‘drop out’ from human immunodeficiency virus (HIV) treatment, the so called lost-to-follow-up (LTFU) occurs to persons enrolled in HIV care services. However, in sub-Saharan Africa (SSA),...

Cryptococcal antigen in serum and cerebrospinal fluid for detecting cryptococcal meningitis in adults living With human immunodeficiency virus: Systematic review and meta-analysis of diagnostic test accuracy studies

2021

Cryptococcal antigen (CrAg) detection could direct the timely initiation of antifungal therapy. We searched MEDLINE and Embase for studies where CrAg detection in serum/cerebrospinal fluid (CSF) and CSF fungal culture...

Rates and risk factors for suicidal ideation, suicide attempts and suicide deaths in persons with HIV: A systematic review and meta-analysis

2021

BACKGROUND: People living with HIV/AIDS (PLWHA) must contend with a significant burden of disease. However, current studies of this demographic have yielded wide variations in the incidence of suicidality (defined...

Clinical and public health implications of HIV-genetic diversity and drug resistance mutations in Angola: A systematic review

2020

HIV-1 genetic diversity and drug resistance mutations (DRMs) remain a public health concern mainly in low- and middle-income countries. In this review, we estimated the HIV-1 molecular evolution over the...

What constitutes a palliative care need in people with serious illnesses across Africa? A mixed-methods systematic review of the concept and evidence

2021

BACKGROUND: Clarity on what constitutes a palliative care need is essential to ensure that health systems and clinical services deliver an appropriate response within Universal Health Coverage. AIM: To synthesise...

Stigma, HIV risk, and access to HIV prevention and treatment services among me who have sex with mem (MSM) in the United States: A scoping review

2021

In light of recent advances in HIV prevention and treatment, we reviewed the literature to understand how different types of stigma impact HIV risk; access to HIV prevention, care, and...

HIV-tuberculous meningitis co-infection: A systematic review and meta-analysis

2021

Human immunodeficiency virus (HIV)-infected persons are at a higher risk of developing Tuberculous meningitis (TBM). We aimed to estimate the prevalence of TBM-HIV co-infection. We systematically searched Pubmed/Medline, Embase and...

Adherence to HIV care and associated health functioning among youth living with HIV in Sub-Saharan Africa

2021

Older adolescents and young adults (youth) living with HIV (YLH) in sub-Saharan Africa (SSA) are at high risk for poor HIV treatment adherence and associated negative health outcomes including viral...

Effectiveness of opiate substitution treatment in reducing HIV risk behaviors among African Caribbean and Black people: A systematic review

2021

OBJECTIVE: The objective of this systematic review is to identify, appraise, and synthesize the best available evidence on the effectiveness of opioid substitution treatment in reducing HIV risk behavior among...

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