Best practices of same-day HIV pre-exposure prophylaxis (PrEP) initiation


  • Several clinics have implemented same-day PrEP programs and have reported that clinics offering this model of care, in general, have positive health outcomes. Studies also report that same-day PrEP is safe and feasible and acceptable to patients.
  • A review of same-day PrEP programs suggests that clinics with this model of care should have the ability to conduct specific point-of-care tests, draw blood for laboratory testing, contact patients, offer navigation services, and provide ongoing PrEP care (either onsite or through referral).
  • One study found that clinical assessment is an adequate method to identify patients eligible for same-day PrEP in settings that do not have access to laboratory testing, suggesting that same-day PrEP is a safe and promising model of care for clinics even with limited capacity.
  • More research is needed to assess retention in PrEP care among patients who are offered a same-day PrEP.


The Ontario HIV Treatment Network: Rapid Response Service




  • Epidemiology and Determinants of Health
    • Determinants of Health
  • Determinants of Health
    • Health services
  • Population(s)
    • General HIV- population
  • Prevention, Engagement and Care Cascade
    • Prevention
  • Prevention
    • Biomedical interventions
  • Testing
    • Testing


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