Category Archives: Co-infections
Tuberculosis-associated mortality and risk factors for HIV-infected population in Ethiopia: A systematic review and meta-analysis
Background: Despite the effectiveness of antiretroviral therapy in reducing mortality from opportunistic infections among people living with HIV (PLHIV), tuberculosis (TB) continues to be a significant cause of death, accounting...
Global epidemiology, natural history, maternal-to-child transmission, and treatment with DAA of pregnant women with HCV: A systematic review and meta-analysis
BACKGROUND: Pregnant Background Pregnant women with hepatitis C virus (HCV) infection represent a special population in which treatment access remains limited despite its increasing prevalence. A reliable estimate of the...
Prevalence of hepatitis B, hepatitis C, and tuberculosis among people living with HIV in Iran: A systematic review and meta-analysis
BACKGROUND: Up to now several studies estimate the prevalence of HBV, HCV, and TB among people living with HIV (PLWH) in Iran; however, their results are inconsistent. This study aimed...
Mortality and associated factors among patients with TB-HIV co-infection in Ethiopia: A systematic review and meta-analysis
Background Tuberculosis (TB) and human immunodeficiency virus (HIV) co-infection is a major public health problem in Ethiopia. Patients with TB-HIV co-infection have significantly higher mortality rates compared to those with...
Incidence density mortality rate among HIV-positive children on antiretroviral therapy in Ethiopia: A systematic review and meta-analysis
BACKGROUND: Human Immunodeficiency Virus (HIV) continues to be the major cause of childhood deaths, particularly in the sub-Saharan African region. In Ethiopia, though several primary studies have been conducted on...
Palliative care considerations for the older adults with HIV/AIDS: A clinical practice review
Human immunodeficiency virus (HIV) has historically been viewed as a terminal condition affecting younger populations, however, with advancements in antiretroviral therapy (ART) and better healthcare provisions, people with HIV are...
Prevalence, incidence, and case fatality of tuberculous meningitis in adults living with HIV: A systematic review and meta-analysis
BACKGROUND: Tuberculous meningitis (TBM) emerges as a grave complication of tuberculosis in people living with HIV (PLWH). The diagnosis and treatment of TBM pose significant challenges, leading to elevated mortality...
A comparison of active pharmacovigilance strategies used to monitor adverse events to antiviral agents: A systematic review
INTRODUCTION: The safety of antiviral agents in real-world clinical settings is crucial, as pre-marketing studies often do not capture all adverse events (AE). Active pharmacovigilance strategies are essential for detecting...
A critical review of mpox outbreaks, risk factors, and prevention efforts in Africa: Lessons learned and evolving practices
OBJECTIVES: In recent years, mpox, a zoonotic disease caused by the mpox virus, has transcended its primary association with Central and West Africa, emerging as a global public health concern....
Disease intervention specialist-delivered interventions and other partner services for HIV and sexually transmitted infections: A systematic review
INTRODUCTION: Disease intervention specialists (DIS) are critical for delivering partner services programs that provide partner notification, counseling, referral, and other services for HIV, sexually transmitted infections (STIs), and other infections....
Using mHealth technologies for case finding in tuberculosis and other infectious diseases in Africa: Systematic review
BACKGROUND: Mobile health (mHealth) technologies are increasingly used in contact tracing and case finding, enhancing and replacing traditional methods for managing infectious diseases such as Ebola, tuberculosis, COVID-19, and HIV....
Perineal disintegration syndrome (PDS) in children with human immunodeficiency virus (HIV) infection: A scoping review
BACKGROUND: Paediatric healthcare for children with HIV involves managing complex challenges, including severe perineal issues that significantly affect their quality of life. We introduce the term “perineal disintegration syndrome” (PDS)...
