Category Archives: Co-infections

Doxycycline prophylaxis for the prevention of bacterial sexually transmitted infections (STIs): doxyPrEP and doxyPEP

2024

No abstract available

Immune responses to vaginal candidiasis in African women: A scoping review of cytokine profiles, T-cell activation, and gene expression

2025

Background Recent immunological studies of vaginal candidiasis in African populations have revealed complex host‒pathogen interactions with implications for therapeutic development and HIV acquisition risk. Objective This scoping review synthesized evidence...

Adolescents’ sexual health during the COVID-19 outbreak: A systematic review

2025

BACKGROUND AND AIMS: The COVID-19 pandemic has greatly disrupted adolescents’ access to sexual health services, resulting in a decline in their overall sexual well-being. This systematic review explored adolescent sexual...

Exploring a rare association: Systematic review of hypercalcemia in nontuberculous mycobacterial infections

2025

Hypercalcemia represents a rare complication of nontuberculous Mycobacterium (NTM) infections, particularly in individuals with human immunodeficiency virus (HIV) positivity. This systematic review examines NTM infections associated with hypercalcemia, including the...

The association between HIV/AIDS, ototoxicity of its treatments, and occupational noise induced hearing loss: A narrative review mapping the existing literature and identifying research gaps

2025

Hearing loss remains a significant but underexplored health challenge in individuals with HIV/AIDS, particularly those exposed to occupational noise. The ototoxic effects of antiretroviral therapy (ART) and comorbid conditions like...

Aging and HIV: Recent findings in contributing factors

2025

Background: Aging among people living with HIV (PLWH) presents multifaceted challenges influenced by antiretroviral therapy (ART), chronic inflammation, viral coinfections, stigma, multimorbidity, and immunosuppression. Methods: This review synthesizes recent research...

Efficacy, immunogenicity, and safety of the Novavax COVID-19 vaccine in immunocompromised patients: A targeted literature review

2025

Individuals who are immunocompromised (IIC) may have impaired infection prevention/resolution, potentially causing increased disease severity, complications, and healthcare-system strain. Exclusion of IIC from COVID-19 vaccine trials and limited real-world Novavax...

Pneumocystis infection in pregnant women: A scoping review

2025

Pneumocystis jirovecii is an opportunistic fungus that causes severe pneumonia in immunosuppressed individuals. While Pneumocystis colonization, a subclinical form of infection, has been studied in different populations, its implications during...

Four decades of overdose prevention centres: Lessons for the future from a realist review

2025

BACKGROUND: Overdose prevention centres (OPCs) are spaces where people can consume previously obtained illicit drugs under the supervision of staff who can intervene to prevent and manage overdose.AÿThey have been...

Global, regional, and national estimates of hepatitis C virus (HCV) infection incidence among people who inject drugs and number of new annual HCV infections attributable to injecting drug use: A multi-stage analysis

2025

Background: Measuring progress towards the WHO 2030 target for hepatitis C virus (HCV) elimination among people who inject drugs (PWID)-an incidence of two or fewer infections per 100 person-years-has been challenging...

Gastrointestinal Escherichia coli in men who have sex with men: A systematic review

2024

OBJECTIVE: This systematic review aimed to explore any demographic, biological and behavioural characteristics of men who have sex with men (MSM) with diarrhoeagenic E.coli. DESIGN/METHODS: We searched MEDLINE, EMBASE, and...

Prevalence of HHV-6 detection among people living with HIV: A systematic review and meta-analysis

2025

Human herpesvirus 6 (HHV-6) is a ubiquitous virus with significant implications for immunocompromised individuals, particularly people living with HIV (PLWH). This study aimed to estimate the prevalence of HHV-6 detection...

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