Category Archives: Hepatitis B, C
The global epidemiology of injecting drug use, HIV, viral hepatitis and tuberculosis among people who are incarcerated: A multistage systematic review
Background: This global systematic review assesses the prevalence of injecting drug use (IDU) and key infectious diseases (HIV, hepatitis C virus [HCV], tuberculosis and hepatitis B virus [HBV]) among people...
Global coverage of interventions for reduction of injecting drug use-related harm, HIV, viral hepatitis and tuberculosis in prisons and other carceral settings: A systematic review
BACKGROUND: People who are incarcerated experience disproportionately high rates of injecting drug use and infectious disease, including HIV, viral hepatitis and tuberculosis. However, comprehensive global data regarding the availability of...
Factors influencing implementation of point-of-care tests for maternal and newborn screening and diagnosis in low-resource settings: A systematic review
BACKGROUND: Despite the potential of point-of-care (POC) tests to improve maternal and newborn health, implementation in low- and middle-income countries remains inconsistent. POC testing enables rapid, decentralized screening, but barriers...
The prevalence and influencing factors of frailty among middle-aged and older adults with HIV/AIDS from a global perspective: A systematic review and meta-analysis
Aim: Currently, frailty has become a central issue in health management among middle-aged and older people living with HIV/AIDS (PLWHA) worldwide. The objective is to develop targeted strategies to improve frailty...
Virus-directed CAR immunotherapies for chronic HBV and HIV: A systematic synthesis of preclinical and early clinical evidences
BACKGROUND: Chronic hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infections are among the most important global health issues. Virus-directed CAR-T and CAR-NK are promising strategies capable of targeting...
Epidemiology and safety challenges of major transfusion-transmitted pathogens in Cameroon: A systematic review and meta-analysis
Objectives: This systematic review and meta-analysis (SRMA) was designed to determine the prevalence, patterns, and determinants of major transfusion-transmitted infections (TTIs), to address this gap, and to propose solutions to...
Harm reduction progams and interventions for equity-deserving populations who use crack-cocaine. A scoping review
BACKGROUND: Crack-cocaine use is associated with severe physical and mental health consequences, including cardiac, pulmonary and psychiatric conditions. It also heightens the risk of overdose and transmission of infectious diseases...
The risk of infection-related malignancies and tumor mutational burden in immunocompromised hosts: A systematic review and meta-analysis
Background Immunocompromised individuals exhibit an increased risk of malignancies attributable to impaired immune surveillance and increased susceptibility to oncogenic infections, resulting in distinct responses to immunotherapy. The intricacies of infection-related...
The prognosis characteristics of HIV/HBV co-infection after antiviral therapy: A comprehensive review
Co-infection of HIV and HBV is still a major global public health concern. Co-infected people have a nearly threefold increased risk of end-stage liver disease, with a noticeably faster development...
Risk prediction models for targeted testing of HIV, hepatitis B and hepatitis C: A systematic review and meta-analysis
Background Diagnosing human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) infections in general population settings is challenging. We conducted a systematic review and meta-analysis of...
Unveiling the underestimated prevalence of HIV, HBV and TB triple infection in Asia, South America, and Africa: A systematic review and meta-analysis
BACKGROUND: Human immunodeficiency virus (HIV) is a genus of retroviruses that targets immune cells and may eventually cause immune-deficiency illness. Triple infection of HIV/hepatitis B virus (HBV) /tuberculosis (TB) leads...
Global human immunodeficiency virus prevalence and risk behaviors in transmasculine Individuals: A scoping review
PURPOSE: This scoping review sought to synthesize human immunodeficiency virus (HIV) and sexually transmitted infection (STI) prevalence, incidence, risk behaviors, and risk perceptions among transmasculine (TM) individuals globally. METHODS: Eligible...
