Category Archives: Hepatitis B, C
Drug interactions with direct-acting antivirals for Hepatitis C: Implications for HIV and transplant patients
OBJECTIVE: Review pharmacokinetics of new direct-acting antivirals (DAAs) for hepatitis C (HCV) infection and interactions with concomitant immunosuppressant and antiretroviral therapies (ART). DATA SOURCES: MEDLINE (1948–January 2015), EMBASE (1964–January 2015),...
Prevalence of non-HIV cancer risk factors in persons living with HIV/AIDS: A meta-analysis
OBJECTIVE: The burden of cancer among persons living with HIV/AIDS (PLWHA) is substantial and increasing. We assessed the prevalence of modifiable cancer risk factors among adult PLWHA in Western high-income...
Epidemiology and impact of HIV coinfection with hepatitis B and hepatitis C viruses in Sub-Saharan Africa
Human immunodeficiency virus (HIV), Hepatitis B (HBV) and Hepatitis C (HCV) are blood-borne viruses with potentially shared routes of transmission. In high-income settings, the impact of antiretroviral therapy (ART) on...
Impact of hepatitis C virus on immune restoration in HIV-infected patients who start highly active antiretroviral therapy: A meta-analysis
BACKGROUND: There are conflicting data in the medical literature regarding the degree of immune restoration (as measured by CD4 cell count) in patients who commence highly active antiretroviral therapy (HAART)...
Awareness and knowledge of sexually transmitted diseases (STDs) among school-going adolescents in Europe: A systematic review of published literature
BACKGROUND: Sexually transmitted diseases (STDs) are a major health problem affecting mostly young people, not only in developing, but also in developed countries.We conducted this systematic review to determine awareness...
Women experience higher rates of adverse events during Hepatitis C virus therapy in HIV infection: A meta-analysis
Background: In HIV/HCV coinfection, adverse events (AE) during HCV therapy account for 12-39% of treatment discontinuations. It is unknown whether sex influences complications. Methods: Meta-analysis to study the effect of...
Peginterferon vs. interferon in the treatment of different HCV genotype infections in HIV patients
It remains difficult to achieve high sustained response rates (SVRs) in chronic hepatitis patients coinfected with human immunodeficiency virus (HIV). The aim of this study was to perform a meta-analysis...
Antiretroviral therapy for children in resource-limited settings: Current regimens and the role of newer agents
WHO antiretroviral treatment guidelines for HIV-infected children have influenced the design of treatment programmes in resource-limited settings. This review analyses the latest WHO first- and second-line regimen recommendations. The recommendation...
