Category Archives: Hepatitis B, C
Treatment, care and support for people co-infected with HIV and hepatitis C: A scoping review
Background: Providing care for people who are co-infected with both HIV and hepatitis C virus (HCV) is becoming increasingly complex and requires integrated prevention, screening, support and programming efforts. We...
Barriers to hepatitis C antiviral therapy in HIV/HCV co-infected patients in the United States: A review
This review synthesized the literature for barriers to HCV antiviral treatment in persons with HIV/HCV co-infection. Searches of PubMed, Embase, CINAHL, and Web of Science were conducted to identify relevant...
HIV and hepatitis B and C incidence rates in US correctional populations and high risk groups: A systematic review and meta-analysis
BACKGROUND: High Human Immunodeficiency Virus (HIV) prevalence and high risk behaviors have been well documented within United States (US) correctional systems. However, uncertainty remains regarding the extent to which placing...
Meta-analysis: Increased mortality associated with hepatitis C in HIV-infected persons is unrelated to HIV disease progression
Background: It is unclear whether coinfection with hepatitis C virus (HCV) increases mortality in patients with human immunodeficiency virus (HIV) infection during the era of highly active antiretroviral therapy (HAART)....
Systematic review and meta-analysis of the diagnostic accuracy of fibrosis marker panels in patients with HIV/hepatitis C coinfection
BACKGROUND: Accurately staging hepatitis C virus (HCV)-related fibrosis is crucial for treatment decisions and prognostication. Our objective was to systematically review studies describing the accuracy of serum marker panels for...
Influence of maternal human immunodeficiency virus (HIV) co-infection on vertical transmission of hepatitis C virus (HCV): A meta-analysis
BACKGROUND: Maternal co-infection with human immunodeficiency virus (HIV) has been implicated as a potentially important co-factor for enhanced vertical transmission of hepatitis C virus (HCV). In previous reports, however, methodological...
Barriers to care and treatment for patients with chronic viral hepatitis in Europe: A systematic review
BACKGROUND & AIMS: Despite the availability of effective therapies for hepatitis B (HBV) and C virus (HCV), only a minority of these patients receive treatment. We systematically reviewed published data...
Liver transplant outcomes in HIV-infected patients: A systematic review and meta-analysis with synthetic cohort
OBJECTIVES: : The relative success of liver transplantation in those with HIV compared to HIV-uninfected individuals remains a point of intense debate. We aimed to evaluate the effectiveness of liver...
The utility of therapeutic drug monitoring for ribavirin in patients with chronic hepatitis C – A critical review
OBJECTIVE: To evaluate the utility of therapeutic drug monitoring (TDM) for ribavirin in chronic hepatitis C. DATA SOURCES: Literature searches were conducted through PubMed (1949-June 2009), EMBASE (1980-June 2009), BIOSIS...
Hepatitis B/C and HIV in sub-Saharan Africa: an association between highly prevalent infectious diseases. A systematic review and meta-analysis
OBJECTIVES: Hepatitis B virus (HBV), hepatitis C virus (HCV), and the human immunodeficiency virus (HIV) are endemic in Africa. However, hepatitis co-infection rates among HIV-infected individuals remain controversial. The aim...
Impact of hepatitis C virus on immune restoration in HIV-infected patients who start highly active antiretroviral therapy: A meta-analysis
BACKGROUND: There are conflicting data in the medical literature regarding the degree of immune restoration (as measured by CD4 cell count) in patients who commence highly active antiretroviral therapy (HAART)...
