Category Archives: Hepatitis B, C

Review of drug interactions with telaprevir and antiretrovirals

2013

HCV infection is a major cause of mortality worldwide. HCV-related deaths also represent a leading cause of mortality in HIV-coinfected individuals. Telaprevir is an NS3/4A protease inhibitor approved for the...

Performance of the aspartate aminotransferase-to-platelet ratio index for the staging of hepatitis C-related fibrosis: An updated meta-analysis

2011

The aspartate aminotransferase-to-platelet ratio index (APRI), a tool with limited expense and widespread availability, is a promising noninvasive alternative to liver biopsy for detecting hepatic fibrosis. The objective of this...

Can hepatitis C virus prevalence be used as a measure of injection-related human immunodeficiency virus risk in populations of injecting drug users? An ecological analysis

2010

BACKGROUND: Human immunodeficiency virus (HIV) outbreaks occur among injecting drug users (IDUs), but where HIV is low insight is required into the future risk of increased transmission. The relationship between...

Effects of interferon-alpha treatment on the incidence of hyperglycemia in chronic hepatitis c patients: A systematic review and meta-analysis

2012

Background: There is a significant association between effects of interferon-alpha treatment and the risk of developing hyperglycemia in patients with chronic hepatitis C virus (HCV) infection. The objective of this...

Prevalence of human immunodeficiency virus/hepatitis C virus co-infection in Brazil and associated factors: A review

2013

The hepatitis C virus and human immunodeficiency virus share the same transmission routes, which makes co-infection an unfavorable condition for the natural history of both viral diseases. In this context,...

Risk of window period hepatitis-C infection in high infectious risk donors: Systematic review and meta-analysis

2011

The OPTN classifies high infectious risk donors (HRDs) based on criteria originally intended to identify people at risk for HIV infection. These donors are sometimes referred to as ‘CDC high...

Meta-analysis: Implications of interleukin-28B polymorphisms in spontaneous and treatment-related clearance for patients with hepatitis C

2013

BACKGROUND: Since 2009, several studies have identified single-nucleotide polymorphisms (SNPs) near the gene encoding for interleukin (IL)-28 (IL28B) that are strongly associated with spontaneous and treatment-induced hepatitis C virus (HCV)...

Kidney and liver organ transplantation in persons with human immunodeficiency virus: An evidence-based analysis

2010

The objective of this analysis is to determine the effectiveness of solid organ transplantation in persons with end stage organ failure (ESOF) and human immunodeficiency virus (HIV+) Clinical Need: Condition...

Prevalence of hepatitis B and C in HIV-infected patients: A meta-analysis

2011

BACKGROUND: Hepatitis C virus (HCV), hepatitis B virus (HBV) and human immunodefciency virus (HIV) share similar routes of transmission by sexual intercourse or drug use by parenteral injection, so coinfection...

People who use drugs, HIV, and human rights

2010

We reviewed evidence from more than 900 studies and reports on the link between human rights abuses experienced by people who use drugs and vulnerability to HIV infection and access...

Natural history of hepatitis C virus infection in HIV-infected individuals and the impact of HIV in the era of highly active antiretroviral therapy: A meta-analysis

2008

Objectives: To estimate stage-specific transition probabilities in individuals coinfected with HIV and hepatitis C virus (HCV), to examine the effect of covariates on these rates, and to investigate the effect...

Management of chronic hepatitis C

2002

Objectives: Hepatitis C is the most common blood-borne infection in the United States and can lead to serious complications including cirrhosis and hepatocellular carcinoma (HCC). The objectives of this report...

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