Category Archives: Other
Acceptability of self-sampling and self-testing for infections: A rapid systematic review on public users’ views
Background Self-sampling and self-testing have been increasingly used for sexually transmitted infections (STIs) and quickly became widespread during the COVID-19 pandemic. User acceptability, preferences, and experiences are important factors affecting...
The efficacy of Cotrimoxazole for the prevention of Pneumocystis jirovecii pneumonia among HIV-exposed and infected children: A systematic review
BACKGROUND: HIV-related opportunistic infections like Pneumocystis jirovecii Pneumonia (PCP) remain a major contributor to child morbidity and mortality globally. PCP accounts for over 60% of AIDS in the first year...
The global prevalence and impact of steatotic liver disease and viral infections: A systematic review and meta-analysis
Background: Steatotic liver disease (SLD) affects ~30% of adults worldwide. The global population is continuously threatened by epidemic and endemic viral diseases. This study aims to thoroughly examine the interaction...
Comprehensive appraisal of the association between sexually transmitted infections and prostate cancer: A scoping review of empirical studies, reviews, and meta-analyses
We performed a scoping review on the association of sexually transmitted infections (STIs) with prostate cancer and identified knowledge gaps. Searching four databases (Medline, Embase, Scopus, and Cochrane) identified 286...
Prevalence of Mpox vaccine acceptance and hesitancy among people living with HIV: A comprehensive systematic review and meta-analysis
Background Vaccine acceptance among People Living with HIV (PLWH) is crucial for managing and mitigating the spread of infectious diseases, including Mpox. This systematic review and meta-analysis assess the rate...
The burden of HPV infections and HPV-related diseases among people with HIV: A systematic literature review
Human papillomavirus (HPV) is associated with a significant global burden of precancerous lesions and cancer. People with HIV (PWH) are at higher risk of HPV infection and HPV‐related diseases. This...
The prevalence of human papillomavirus (HPV) genotypes in the oral mucosae of HIV-positive individuals: A systematic review and meta-analysis
Papillomaviruses are double-stranded DNA viruses, and it is essential to clarify their genotypic distribution for their effective prevention and clinical management. In this study, we aimed to evaluate the prevalence...
Diagnostic tests performance in detecting Pneumocystis jirovecii: A systematic review and meta-analysis
BACKGROUND AND OBJECTIVE: Pneumocystis jirovecii (Pj) pneumonia (PJP) is a life-threatening opportunistic infection primarily affecting immunocompromised individuals. Detecting Pj is challenging, particularly in distinguishing between Pj colonization (PJC) and infection....
Causes of hospitalisation among people living with HIV worldwide, 2014-23: A systematic review and meta-analysis
Background: Despite improved access to antiretroviral therapy (ART), HIV-related morbidity and mortality remain high. A previous review (2007-14) found that AIDS-related illnesses were the leading causes of hospitalisations. We aimed to...
Prevalence and predictors of virological failure among the people living with HIV on antiretroviral treatment in East Africa: Evidence from a systematic review with meta-analysis and meta-regression of published studies from 2016 to 2023
Background: Virological failure (VF) significantly threatens the efficacy of antiretroviral therapy (ART) programs in East Africa. This systematic review and meta-analysis assess the prevalence and predictors of VF among individuals living...
Risk factors and mortality outcomes of COVID-19 in people living with HIV: A systematic review and meta-analysis
This study was performed to reveal the risk factors associated with mortality in people living with HIV (PLHIV) who were diagnosed with COVID-19. Studies reporting deaths among PLHIV and infected...
The impact of HPV/HIV co-infection on immunosuppression, HPV genotype, and cervical cancer biomarkers
BACKGROUND: Human papillomavirus (HPV) and human immunodeficiency virus (HIV) co-infection present a significant impact on women’s health globally, especially in immunocompromised individuals. HIV-induced immunosuppression promotes the persistence of high-risk HPV...
