Category Archives: Other

Emerging sexually transmitted viral infections: Review of human T-lymphotropic virus-1 disease

2020

No abstract available

Cryptococcal antigenemia and its predictors among HIV infected patients in resource limited settings: A systematic review

2020

BACKGROUND: Cryptococcosis is an opportunistic fungal infection that primarily affects people with advanced HIV/AIDS and is an important cause of morbidity and mortality around the globe. By far the most...

The prevalence of cryptococcal antigen (CrAg) and benefits of pre-emptive antifungal treatment among HIV-infected persons with CD4+ T-cell counts < 200 cells/muL: Evidence based on a meta-analysis

2020

BACKGROUND: Current WHO guidelines (2018) recommend screening for cryptococcal antigen (CrAg) in HIV-infected persons with CD4+ T cell counts< 100 cells/muL, followed by pre-emptive antifungal therapy among CrAg positive (CrAg+)...

Cryptococcal meningitis: A review of cryptococcal antigen screening programs in Africa

2020

INTRODUCTION: Cryptococcal meningitis remains a significant contributor to AIDS-related mortality despite widened access to antiretroviral therapy. Cryptococcal antigen (CrAg) can be detected in the blood prior to development of meningitis....

What is the most appropriate induction regimen for the treatment of HIV-associated Cryptococcal meningitis when the recommended regimen is not available? Evidence from a network meta-analysis

2020

Aims: Our object was to find the most appropriate, most effective, and most readily available of four induction regimens for HIV-associated cryptococcal meningitis (CM) (Regimen A: 1 week of AmB...

Clostridium difficile in immunocompromised hosts: A review of epidemiology, risk factors, treatment, and prevention

2019

Clostridium difficile is a significant pathogen in healthcare today, impacting both hospitalized and community-based patients. Immunocompromised patients experience a high incidence of C. difficile infection, ranging from 6% to 33%...

Burden of Talaromyces marneffei infection in people living with HIV/AIDS in Asia during ART era: A systematic review and meta-analysis

2020

BACKGROUND: Talaromyces marneffei (TM) is a dimorphic fungus mainly prevalent in Southeast Asian countries, which often causes disseminated life-threatening infection. TM infection often occurs in HIV/AIDS patients even in the...

A systematic review and meta-analysis to assess the association between urogenital schistosomiasis and HIV/AIDS infection

2020

BACKGROUND: Urogenital schistosomiasis and HIV/AIDS infections are widespread in sub-Saharan Africa (SSA) leading to substantial morbidity and mortality. The co-occurrence of both diseases has led to the possible hypothesis that...

Treating progressive disseminated histoplasmosis in people living with HIV

2020

BACKGROUND: Progressive disseminated histoplasmosis (PDH) is a serious fungal infection that affects people living with HIV. The best way to treat the condition is unclear. OBJECTIVES: We assessed evidence in...

Nature and extent of hearing loss in HIV-infected children: A scoping review

2020

INTRODUCTION: Antiretroviral therapy (ART) has had a major impact on life expectancy from HIV as many people now live with it as a chronic disease. Chronic HIV has been associated...

The global prevalence of hepatitis D virus infection: Systematic review and meta-analysis

2020

BACKGROUND AND AIMS: There are uncertainties about the epidemic patterns of hepatitis delta virus (HDV) infection and its contribution to the burden of liver disease. We estimated the global prevalence...

The interplay of HIV and human papillomavirus-related cancers in sub-Saharan Africa: Scoping review

2020

BACKGROUND: People living with HIV (PLHIV) are at a high risk of developing HPV-related cancers. HPV-related malignancies occur frequently and/or are high among PLHIV, with cervical cancer as a designated...

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