Category Archives: Other
Bacterial co-infections in HIV/AIDS-positive subjects: A systematic review and meta-analysis
BACKGROUND: Bacterial infections are the most common complications in people with HIV/AIDS. There has been no previous report on the prevalence of bacterial co-infections in Iranian HIV/AIDS-positive subjects. AIM: To...
Trichomonas vaginalis and HIV infection acquisition: A systematic review and meta-analysis
OBJECTIVES: Trichomoniasis is the most prevalent curable STI globally, with the highest incidence and prevalence in sub-Saharan Africa (sSA). STIs have largely been associated with an increase in HIV acquisition....
Histoplasma capsulatum antigen detection tests as an essential diagnostic tool for patients with advanced HIV disease in low and middle income countries: A systematic review of diagnostic accuracy studies
INTRODUCTION: Disseminated histoplasmosis, a disease that often resembles and is mistaken for tuberculosis, is a major cause of death in patients with advanced HIV disease. Histoplasma antigen detection tests are...
A systematic review of the efficacy and safety of fecal microbiota transplant for clostridium difficile infection in immunocompromised patients
Background: Fecal microbiota transplantation (FMT) has been shown to be effective in recurrent Clostridium difficile (CD) infection, with resolution in 80% to 90% of patients. However, immunosuppressed patients were often...
Type-specific anal human papillomavirus prevalence among men, according to sexual preference and HIV status: A systematic literature review and meta-analysis
Background: Anal human papillomavirus (HPV) infection, most notably of HPV16, the central cause of anal cancer, is increased by anal sexual intercourse and worsened by HIV-positivity. Methods: We undertook a...
Morbidity benefit conferred by childhood immunisation in relation to maternal HIV status: A meta-analysis of demographic and health surveys
The study determined the prevalence of acute respiratory infections and diarrhoea among sub-Saharan African children. It also examined if there was any significant morbidity benefit conferred by three doses of...
Early versus delayed antiretroviral treatment in HIV-positive people with cryptococcal meningitis
BACKGROUND: There remains uncertainty about the optimum timing of antiretroviral therapy (ART) initiation in HIV-positive people with cryptococcal meningitis. This uncertainty is the result of conflicting data on the mortality...
Impact of routine cryptococcal antigen screening and targeted pre-emptive fluconazole therapy in antiretroviral naive HIV-infected adults with less than 100 CD4 cells/muL: A systematic review and meta-analysis
Cryptococcal antigen (CrAg) screening and targeted pre-emptive fluconazole in antiretroviral naive HIV-infected adults with less than 100 CD4 cells/muL seems promising to reduce the burden of cryptococcal meningitis (CM). We...
Evidence of synergistic relationships between HIV and Human Papillomavirus (HPV): Systematic reviews and meta-analyses of longitudinal studies of HPV acquisition and clearance by HIV status, and of HIV acquisition by HPV status
INTRODUCTION: Observational studies suggest HIV and human papillomavirus (HPV) infections may have multiple interactions. We reviewed the strength of the evidence for the influence of HIV on HPV acquisition and...
Incidence of invasive pneumococcal disease in immunocompromised patients: A systematic review and meta-analysis
BACKGROUND: Invasive pneumococcal disease (IPD) is associated with high morbidity and mortality, with immunocompromised patients (ICPs) at particular risk. Therefore, guidelines recommend pneumococcal vaccination for these patients. However, guidelines are...
