Category Archives: Other
Primary prophylaxis for cryptococcal meningitis and impact on mortality in HIV: A systematic review and meta-analysis
Aim: To determine the role of primary antifungal prophylaxis in the prevention of cryptococcal meningitis and all-cause mortality in advanced HIV infection. Materials & methods: This was a systematic review...
The impact of water, sanitation, and hygiene interventions on the health and well-being of people living with HIV: A systematic review
BACKGROUND: Access to improved water supply and sanitation is poor in low-income and middle-income countries. Persons living with HIV/AIDS (PLHIV) experience more severe diarrhea, hospitalizations, and deaths from diarrhea because...
Discontinuing pneumocystis jirovecii pneumonia prophylaxis in HIV-infected patients with a CD4 cell count <200 cells/mm3
OBJECTIVE: To review the evidence for discontinuing primary and secondary Pneumocystis jirovecii pneumonia (PJP) prophylaxis in HIV-infected patients with a CD4 count <200 cells/mm3. DATA SOURCES: We conducted a literature...
Efficacy of inactivated hepatitis a vaccine in HIV-infected patients: A hierarchical Bayesian meta-analysis
Patients with human immunodeficiency virus-1 (HIV) have elevated risk for hepatitis A virus (HAV) coinfection. Sequelae from coinfection include increased risk of liver-related morbidity and mortality. This study synthesizes the...
HIV and human herpesvirus 8 co-infection across the globe: Systematic review and meta-analysis
HIV-infection is an important risk factor for developing Kaposi sarcoma (KS), but it is unclear whether HIV-positive persons are also at increased risk of co-infection with human herpesvirus 8 (HHV-8),...
Single use of Iitraconazole has no effect on treatment for Penicillium marneffei with HIV infection
OBJECTIVE: To evaluate the efficacy of a single use of itraconazole for treating Penicillium marneffei infection in HIV-infected patients, help to develop a clinical medication regimen, and provide a scientific...
The effect of sexually transmitted co-infections on HIV viral load amongst individuals on antiretroviral therapy: A systematic review and meta-analysis
BACKGROUND: Antiretroviral therapy (ART) markedly reduces HIV transmission, and testing and treatment programs have been advocated as a method for decreasing transmission at the population level. Little is known, however,...
Leishmaniasis as a manifestation of immune reconstitution inflammatory syndrome (IRIS) in HIV-infected patients: A literature review
INTRODUCTION: After the onset of highly active antiretroviral therapy (HAART), some HIV-infected patients present a severe inflammation in response to a latent or a previously treated opportunistic pathogen termed immune...
Causes of hospital admission among people living with HIV worldwide: A systematic review and meta-analysis
BACKGROUND: Morbidity associated with HIV infection is poorly characterised, so we aimed to investigate the contribution of different comorbidities to hospital admission and in-hospital mortality in adults and children living...
Risk factors for multidrug resistant tuberculosis in Europe: A systematic review
BACKGROUND: The resurgence of tuberculosis (TB) in western countries has been attributed to the HIV epidemic, immigration, and drug resistance. Multidrug resistant tuberculosis (MDR-TB) is caused by the transmission of...
