Category Archives: Other
Abstinence-plus programs for HIV infection prevention in high-income countries
BACKGROUND: Abstinence-plus interventions promote sexual abstinence as the best means of preventing acquisition of HIV, but also encourage safer-sex strategies (eg condom use) for sexually active participants. OBJECTIVES: To assess...
Intravaginal practices, bacterial vaginosis, and women’s susceptibility to HIV infection: Epidemiological evidence and biological mechanisms
Intravaginal practices such as “dry sex” and douching have been suggested as a risk factor that may increase women’s susceptibility to HIV infection. These behaviours appear common in different populations...
Discontinuation of Pneumocystis jirovecii pneumonia prophylaxis with CD4 count <200 cells/mul and virologic suppression: A systematic review
Background: HIV viral load (VL) is currently not part of the criteria for Pneumocystis jirovecii pneumonia (PCP) prophylaxis discontinuation, but suppression of plasma viremia with antiretroviral therapy may allow for...
Pulmonary resection for patients with multidrug-resistant tuberculosis: Systematic review and meta-analysis
OBJECTIVES: Multidrug-resistant tuberculosis (MDR-TB) has become an emerging global public health crisis. Several studies have suggested that pulmonary resection has efficacy in the treatment of MDR-TB. A systematic review of...
Does trimethoprim-sulfamethoxazole prophylaxis for HIV induce bacterial resistance to other antibiotic classes? Results of a systematic review
BACKGROUND: Trimethoprim-sulfamethoxazole (TMP-SMX) prophylaxis has long been recommended for immunosuppressed HIV-infected adults and children born to HIV-infected women. Despite this, many resource-limited countries have not implemented this recommendation, partly because...
Intravaginal practices, bacterial vaginosis, and HIV infection in women: Individual participant data meta-analysis
BACKGROUND: Identifying modifiable factors that increase women’s vulnerability to HIV is a critical step in developing effective female-initiated prevention interventions. The primary objective of this study was to pool individual...
Evidence behind the WHO guidelines: Hospital Care for Children: The usefulness of azole prophylaxis against cryptococcal meningitis in HIV-positive children
The World Health Organization has produced guidelines for the management of common illnesses in hospitals with limited resources. This series reviews the scientific evidence behind WHO’s recommendations. The WHO guidelines...
Multifocal Epstein-Barr Virus-associated smooth muscle tumor in adults with AIDS: Case report and review of the literature
Objectives: The aim of this study was to provide a systematic review of Epstein-Barr virus-associated smooth muscle tumors (EBV-SMT) in human immunodeficiency virus (HIV)-infected adults, focusing on clinical and histopathologic...
Performance of commercial herpes simplex virus type-2 antibody tests using serum samples from Sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: Several commercial type-specific serologic tests are available for herpes simplex virus type 2 (HSV-2). Poor specificity of some tests has been reported on samples from sub-Saharan Africa. METHODS: To...
