Category Archives: Other
Nonoxynol-9 for preventing vaginal acquisition of sexually transmitted infections by women from men
BACKGROUND: The incidence and prevalence of sexually transmitted infections (STI) and other reproductive tract infections (RTI) is high in much of the developing and parts of the developed worlds. STIs...
Meta-analysis of diagnostic procedures for Pneumocystis carinii pneumonia in HIV-1-infected patients
Sputum induction is a simple and noninvasive procedure for Pneumocystis carinii pneumonia (PCP) diagnosis in human immunodeficiency virus-1-positive patients, although less sensitive than bronchoalveolar lavage (BAL). In order to obtain...
Systematic review on the etiology and antibiotic treatment of pneumonia in human immunodeficiency virus-infected children
BACKGROUND: Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality in human immunodeficiency virus (HIV)-infected children. OBJECTIVES AND METHODS: A systematic review of studies that were published between...
Efficacy and safety of micafungin for invasive candida infections: A meta-analysis of randomized controlled trials
Background Invasive fungal infections such as candidiasis and mold infections cause significant morbidity and mortality in seriously ill patients. Micafungin is an echinocandin antifungal agent with potent activity against most...
Burden of HIV-related CMV retinitis in resource-limited settings: A systematic review
Background. Cytomegalovirus (CMV) is a late stage opportunistic infection in people living with HIV/AIDS. Lack of ophthalmological diagnostic skills or convenient CMV treatment and increasing access to antiretroviral therapy, have...
Radiographic features of paediatric pneumocystis pneumonia — A historical perspective
AIM: To determine differences between the plain radiographic features of paediatric pneumocystis pneumonia (PCP) recorded before the emergence of human immunodeficiency virus (HIV) in 1982 and those documented in the...
A systematic review of the effectiveness of antifungal drugs for the prevention and treatment of oropharyngeal candidiasis in HIV-positive patients
OBJECTIVE: A systematic review of randomized clinical trials published between 1966 and April 2000 was undertaken to determine the strength of evidence for the effectiveness of antifungal drugs (nystatin, clotrimazole,...
Active and passive surveillance of yellow fever vaccine 17D or 17DD-associated serious adverse events: Systematic review
Purpose: To identify the rate of serious adverse events attributable to yellow fever vaccination with 17D and 17DD strains reported in active and passive surveillance data. Methods: We conducted a...
The effectiveness of pneumococcal polysaccharide vaccines in adults: A systematic review of observational studies and comparison with results from randomised controlled trials
The use of pneumococcal polysaccharide vaccine has remained controversial since licensure, especially in the elderly. Observational studies form much of the evidence base. We conducted a systematic review of observational...
Isoniazid preventive therapy and risk for resistant tuberculosis
In the context of tuberculosis (TB) resurgence, isoniazid preventive therapy (IPT) is increasingly promoted, but concerns about the risk for development of isoniazid-resistant tuberculosis may hinder its widespread implementation. We...
Invasive non-typhoidal salmonella disease: An emerging and neglected tropical disease in Africa
Invasive strains of non-typhoidal salmonellae have emerged as a prominent cause of bloodstream infection in African adults and children, with an associated case fatality of 20-25%. The clinical presentation of...
