Category Archives: Syphilis
Safety of longer-term doxycycline use: A systematic review and meta-analysis with implications for bacterial sexually transmitted infection chemoprophylaxis
BACKGROUND: Sexually transmitted infections (STIs) such as syphilis, gonorrhea, and chlamydia have significantly increased over the past decade in the United States. Doxycycline as chemoprophylaxis (i.e., postexposure prophylaxis) offers promise...
Systematic review of prevalence and risk factors of transfusion transmissible infections among blood donors, and blood safety improvements in Southern Africa
Blood and blood products are listed as one of the essential medicines by the World Health Organization (WHO). In addition to inadequate supply, most sub-Saharan Africa (SSA) nations fail to...
Non-pharmacological interventions for the prevention of sexually transmitted infections (STIs) in older adults: A systematic review
BACKGROUND: STIs in older adults (adults aged 50 years and older) are on the rise due to variable levels of sex literacy and misperceived susceptibility to infections, among other factors....
The application of systems thinking to the prevention and control of sexually transmissible infections among adolescents and adults: A scoping review
Systems thinking is a mechanism for making sense of complex systems that challenge linear explanations of cause-and-effect. While the prevention and control of sexually transmissible infections (STIs) has been identified...
Men who have sex with men and risk for transfusion-transmissible infections in blood donors in Western countries: A systematic review update
Background and objectives: This systematic review update summarizes evidence concerning transfusion-transmissible infections (TTIs) in male blood donors reporting sex with another man (MSM) or after easing the MSM deferral period. Materials...
Progress towards triple elimination of mother-to-child transmission of HIV, hepatitis B and syphilis in Pacific Island Countries and Territories: A systematic review
The diverse geographic, demographic, and societal factors in the Pacific Island Countries and Territories (PICTs) have contributed to unique epidemiological patterns of HIV, syphilis, and hepatitis B. Transmission can be...
Integration of sexually transmitted infection and HIV pre-exposure prophylaxis services in sub-Saharan Africa: A scoping review
BACKGROUND: Persons living in sub-Saharan Africa (SSA) face disproportionate risk from overlapping epidemics of HIV and bacterial sexually transmitted infections (STIs). Pre-exposure prophylaxis (PrEP) for prevention is gradually being scaled...
The burden of chlamydia, gonorrhea, and syphilis in older adults in the United States: A systematic review
BACKGROUND: Increases in life expectancy, the availability of sexual performance enhancing medication, and changes in sexual partnering suggest that sexually transmitted infections (STIs) among older persons could be on the...
Prevalence of human immunodeficiency virus, syphilis, and hepatitis B and C virus infections in pregnant women: A systematic review and meta-analysis
BACKGROUND: At the 74th World Health Assembly, the WHO issued a strategy for the prevention and control of several major infectious diseases. To achieve the WHO-initiated targets for these infectious...
