Category Archives: Tuberculosis
The global epidemiology of injecting drug use, HIV, viral hepatitis and tuberculosis among people who are incarcerated: a multistage systematic review
BACKGROUND: This global systematic review assesses the prevalence of injecting drug use (IDU) and key infectious diseases (HIV, hepatitis C virus [HCV], tuberculosis and hepatitis B virus [HBV]) among people...
Effectiveness of empiric tuberculosis treatment for presumptive smear-negative pulmonary TB among people living with HIV, a systematic narrative review
INTRODUCTION: Timely diagnosis and prompt initiation of treatment are crucial for the effective management of tuberculosis (TB), particularly in People living with HIV (PLHIV). A delay in diagnosing TB,in this...
Strategies to integrate non-communicable disease interventions in HIV and tuberculosis care contexts in low- and middle-income countries: a scoping review
INTRODUCTION: Integration of management of tuberculosis (TB) and HIV with prevention and treatment of non-communicable diseases (NCDs) is a global priority. However, delivering the full spectrum of HIV/TB and NCD...
Rifapentine-isoniazid versus isoniazid-alone therapy for tuberculosis prevention among people living with HIV (PLHIV): a systematic review and meta-analysis of randomized trials
INTRODUCTION: Tuberculosis (TB), a substantial cause of morbidity and mortality among people living with human immunodeficiency virus (PLHIV), accounted for 161,000 deaths among HIV-co-infected patients in 2023. Tuberculosis preventive therapy...
Global coverage of interventions for reduction of injecting drug use-related harm, HIV, viral hepatitis and tuberculosis in prisons and other carceral settings: A systematic review
BACKGROUND: People who are incarcerated experience disproportionately high rates of injecting drug use and infectious disease, including HIV, viral hepatitis and tuberculosis. However, comprehensive global data regarding the availability of...
HIV Mortality Surveillance in Nigeria, A Systematic Review of Trends, Determinants, and Implications For Public Health Policy
Despite substantial progress in expanding antiretroviral therapy (ART) coverage and scaling up prevention interventions, Human Immunodeficiency Virus (HIV) related mortality remains a significant public health challenge in several high-burden settings,...
Effect of BMI on Mortality in Patients With Tuberculosis and HIV Coinfection in Asia and Africa: Systematic Review and Meta-Analysis
BACKGROUND: Tuberculosis (TB) continues to pose a major global health threat, particularly in low- and middle-income countries. An estimated 10.8 million people developed TB in 2023, corresponding to 134 cases...
Risk factors and mortality rates for children co-infected with HIV and TB in Ethiopia: a systematic review and meta-analysis
This systematic review and meta-analysis aimed to identify risk factors and mortality rates in HIV and TB co-infected children in Ethiopia. An electronic literature search was conducted using multiple databases,...
Gender-responsive and -transformative interventions in HIV, TB and malaria programmes: A review of evidence
Gender-responsive and -transformative interventions are essential for tackling harmful social norms and discriminatory laws, policies, and practices that drive gender inequalities and health inequities especially for women, girls, and gender-diverse...
Factors associated with severity of pulmonary tuberculosis in people living with and without HIV: A systematic review
Introduction Tuberculosis is a leading infectious cause of death and morbidity in people with and without HIV. Better identification of severe forms could help target early interventions to reduce mortality...
Pharmacogenetics in tuberculosis-HIV coinfected populations: A systematic review of genetic variants influencing antiretroviral and anti-tuberculosis drug response
Pharmacogenetics is a concept designed to tailor medication based on genetic profile to improve efficacy and reduce adverse effects. This personalized strategy shows considerable potential for populations facing complicated therapeutic...
Prevalence of current substance and hazardous alcohol use among people with HIV and tuberculosis disease and its impact on tuberculosis treatment outcomes: A systematic review
Objective: To examine the prevalence of current substance and hazardous alcohol use in people with HIV and tuberculosis (TB) disease and its impact on TB treatment outcomes. Methods: A systematic review following...
