Category Archives: Tuberculosis
Mortality and its predictors among HIV infected patients taking antiretroviral treatment in Ethiopia: A systematic review
Background: Even though the benefit of antiretroviral therapy (ART) is well established, there is a regional variation in the extent of its benefit. The aim of this review is to...
Estimating the prevalence of positive tuberculin skin test reactions in general population and high-risk groups: A meta-analysis
Results of tuberculin skin test (TST) surveys among different populations have been reported in many studies as a method for detecting primary Mycobacterium tuberculosis infection. Combining these results provides reliable...
Contingency management interventions for HIV, tuberculosis, and hepatitis control among individuals with substance use disorders: A systematized review
Hepatitis, HIV and tuberculosis are significant and costly public health problems that disproportionately affect individuals with substance use disorders (SUDs). Incentive-based treatment approaches (i.e., contingency management; CM) are highly effective...
HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality
BACKGROUND: International human migration has been rapidly growing. Migrants coming from low and middle income countries continue to be considerably vulnerable and at higher risk for infectious diseases, namely HIV...
Antiretroviral therapy in HIV infected children with tuberculosis: A systematic review
BACKGROUND: Tuberculosis is the major cause of mortality in HIV-infected children globally. Current guidelines about the management of antiretroviral therapy in children with tuberculosis are based on a limited number...
Global epidemiology of HIV infection and related syndemics affecting transgender people
INTRODUCTION: Transgender populations have been underrepresented in HIV epidemiologic studies and consequently in HIV prevention, care, and treatment programs. Since 2012, there has been a dramatic increase in research focused...
Accuracy of the interferon-gamma release assay for the diagnosis of active tuberculosis among HIV-seropositive individuals: A systematic review and meta-analysis
BACKGROUND: Although the interferon-gamma release assay (IGRA) has become a widely accepted means for the diagnosis of latent tuberculosis infection (LTBI), the role of the IGRA in diagnosing active tuberculosis...
Initiation and completion rates for latent tuberculosis infection treatment: A systematic review
BACKGROUND: Control of latent tuberculosis infection (LTBI) is an important step towards tuberculosis elimination. Preventive treatment will prevent the development of disease in most cases diagnosed with LTBI. However, low...
Adverse drug reactions during drug-resistant TB treatment in high HIV prevalence settings: A systematic review and meta-analysis
Objectives: To estimate the prevalence of adverse drug reactions or events (ADR) during drug-resistant TB (DR-TB) treatment in the context of settings with high HIV prevalence (at least 20% of...
Clinical management of adults and children with multidrug-resistant and extensively drug-resistant tuberculosis
BACKGROUND: Globally there is a burgeoning epidemic of drug monoresistant tuberculosis (TB), multidrug-resistant TB (MDR-TB) and extensively drug-resistant TB (XDR-TB). Almost 20% of all TB strains worldwide are resistant to...
Adverse effects of oral second-line antituberculosis drugs in children
INTRODUCTION: Increasing numbers of children with drug-resistant tuberculosis are accessing second-line antituberculosis drugs; these are more toxic than first-line drugs. Little is known about the safety of new antituberculosis drugs...
