Category Archives: Co-infections

The effect of HIV and mpox co-infection on clinical outcomes: Systematic review and meta-analysis

2024

Introduction: Co-infection with HIV and mpox is a significant issue for public health because of the potential combined impact on clinical outcomes. However, the existing literature lacks a comprehensive synthesis of...

Rapid systematic review of interventions to improve antenatal screening rates for syphilis, hepatitis B, and HIV in low- and middle-income countries

2024

Background: Infectious diseases including syphilis, HIV, and hepatitis B are major contributors to maternal and neonatal morbidity and mortality worldwide, especially in low- and middle-income countries (LMICs). The World Health Organization...

The pandemics of mass destruction: A Comparative analysis of HIV/AIDS and Coronavirus (COVID-19)

2024

Historically, humanity has suffered and endured deadly pandemics of varying mortality rates. Irrefutably, research shows that the outbreak of pandemics is flooded by mythical and fallacious information among the public,...

Economic evaluations of establishing opioid overdose prevention centers in 12 North American cities: A systematic review

2024

OBJECTIVES: Overdose prevention centers (OPCs) provide a safe place where people can consume preobtained drugs under supervision so that a life-saving medical response can be provided quickly in the event...

A systematic review and meta-analysis of sexually transmitted infections and blood-borne viruses in travellers

2024

Background: Sexually transmitted infections (STIs) and blood-borne viruses (BBVs) impose a global health and economic burden. International travellers facilitate the spread of infectious diseases, including STIs. Hence, this review assessed the...

Disparities in COVID-19 mortality amongst the immunosuppressed: A systematic review and meta-analysis for enhanced disease surveillance

2024

Background Effective disease surveillance, including that for COVID-19, is compromised without a standardised method for categorising the immunosuppressed as a clinical risk group. Methods We conducted a systematic review and...

Impact of harm minimization interventions on reducing blood-borne infection transmission and some injecting behaviors among people who inject drugs: An overview and evidence gap mapping

2024

Background This study aimed to synthetize the evidence on the effectiveness of harm minimization interventions on reducing blood-borne infection transmission and injecting behaviors among people who inject drugs (PWID) through...

Combined “Test and Treat” campaigns for human immunodeficiency virus, hepatitis B, and hepatitis C: A systematic review to provide evidence to support World Health Organization treatment guidelines

2024

BACKGROUND: Worldwide, more than 39 million individuals are living with human immunodeficiency virus (HIV), 296 million with chronic hepatitis B (HBV), and 58 million with chronic hepatitis C (HCV). Despite...

Association between genital mycoplasmas (Ureaplasma urealyticum and Mycoplasma hominis) and HIV infection: A systematic review and meta-analysis

2023

Several studies have reported the occurrence of genital mycoplasmas (Ureaplasma urealyticum, Mycoplasma hominis, Mycoplasma genitalium, and Mycoplasma fermentans) among human immunodeficiency virus (HIV)-infected patients, but findings are conflicting. The aim...

Factors and presenting symptoms associated with intestinal spirochaetosis in men who have sex with men: A systematic review

2024

The transmission dynamics and presenting symptoms of intestinal spirochaetosis (Brachyspira pilosicoli, Brachyspira aalborgi) are poorly understood but is seen more frequently in men who have sex with men (MSM) where...

Facility-based indicators to manage and scale up cervical cancer prevention and care services for women living with HIV in sub-Saharan Africa: A three-round online Delphi consensus method

2024

BACKGROUND: Of women with cervical cancer (CC) and HIV, 85% live in sub-Saharan Africa, where 21% of all CC cases are attributable to HIV infection. We aimed to generate internationally...

Immune responses to mRNA-based vaccines given as athird COVID-19 vaccine dose in people living with HIV-a literature review

2024

People living with HIV (PLWH) were not included in the first efficacy studies of mRNA vaccines against SARS-CoV-2. In this literature review, we investigate evidence of humoral and cellular immunity...

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