Category Archives: Co-infections
Timing of antiretroviral therapy for HIV in the setting of TB treatment
The convergent human immunodeficiency virus (HIV) and tuberculosis (TB) pandemics continue to collectively exact significant morbidity and mortality worldwide. Highly active antiretroviral therapy (HAART) has been a critical component in...
Use of anti-retroviral therapy in tuberculosis patients on second-line anti-TB regimens: A systematic review
INTRODUCTION: Use of antiretroviral therapy (ART) during treatment of drug susceptible tuberculosis (TB) improves survival. However, data from HIV infected individuals with drug resistant TB are lacking. Second line TB...
Antiretroviral therapy for prevention of tuberculosis in adults with HIV: A systematic review and meta-analysis
BACKGROUND: Human immunodeficiency virus (HIV) infection is the strongest risk factor for developing tuberculosis and has fuelled its resurgence, especially in sub-Saharan Africa. In 2010, there were an estimated 1.1...
High prevalence of drug-resistant tuberculosis and other mycobacteria among HIV-infected patients in Brazil: A systematic review
There is a little-noticed trend involving human immunodeficiency virus (HIV)-infected patients suspected of having tuberculosis: the triple-treatment regimen recommended in Brazil for years has been potentially ineffective in over 30%...
A systematic review of the clinical significance of pulmonary Mycobacterium kansasii isolates in HIV infection
Guidelines recommend treating HIV-infected patients with pulmonary Mycobacterium kansasii infection only in the presence of multiple positive cultures and clinical and radiographic abnormalities. Some authors suggest a single positive culture...
Risk of human immunodeficiency virus infection in herpes simplex virus type 2-seropositive persons: A meta-analysis
To determine the contribution of herpes simplex type 2 (HSV-2) infection to the risk of human immunodeficiency virus (HIV) acquisition, a systematic review of literature and data synthesis were done....
Social network-based interventions to promote condom use: A systematic review
Effective sexually transmitted infection (STIs)/HIV prevention programs are urgently needed, but translating evidence-based methods of STI/HIV prevention into sustainable programs has been difficult. Social influences are critical for establishing condom...
HIV infection and sexual risk behaviour among youth who have experienced orphanhood: Systematic review and meta-analysis
BACKGROUND: Previous research has suggested that orphaned children and adolescents might have elevated risk for HIV infection. We examined the state of evidence regarding the association between orphan status and...
