Category Archives: Co-infections
Vaccination coverage among individuals receiving HIV pre-exposure prophylaxis (PrEP): A systematic review and meta-analysis
Objective: This study aimed to assess vaccination coverage among individuals receiving HIV pre-exposure prophylaxis (PrEP). Methods: A systematic review and meta-analysis were conducted following PRISMA guidelines. PubMed, Scopus, and Web of Science...
HPV vaccination in people living with HIV: A network meta-analysis highlighting safety, immunogenicity, and evidence gaps
Background: HPV infection is a major contributor to cervical and other anogenital cancers, with people living with HIV (PLWH) at particularly high risk due to persistent infection. Although prophylactic HPV vaccines...
Incidence and predictors of mortality among adults on antiretroviral therapy in Ethiopia: A systematic review and meta-analysis
BACKGROUND: Despite the United Nations’ plan to end Human Immunodeficiency Virus (HIV) as a public health concern by 2030, it remains a significant issue in low-income countries, including Ethiopia. Currently,...
Burden of malaria-HIV coinfection and associated adverse outcomes in Ethiopia: A systematic review and meta-analysis
Background The co-occurrence of malaria and HIV represents a significant health crisis in sub-Saharan Africa, particularly in Ethiopia, where both diseases are prevalent. This synergistic burden aggravates health inequalities, strains...
Burden and clinical impact of ‘neglected’ transfusion-transmitted infections in Cameroon: A systematic review and meta-analysis
Background Blood supply is a public health challenge in African countries. In Cameroon, blood selection guidelines focus on four viral and bacterial pathogens (HIV, hepatitis B and C viruses, Treponema pallidum)...
Prevalence of HIV and hepatitis B co-infection in Nigeria: A systematic review and meta-analysis
Introduction Hepatitis B virus (HBV) and Human Immunodeficiency virus (HIV) infections are both major public health concerns in sub-Saharan Africa. Co-infection with these virus accelerates liver disease progression, increases hepatotoxicity,...
Healthcare access in chemsex contexts in Brazil: A scoping review and the VIP-chemsex model
Background/Objectives: Sexualized drug use (SDU) and chemsex have emerged as a growing public health concern globally, reflecting complex intersections between sexual practices, psychoactive substance use, and structural vulnerabilities. In Brazil, however,...
Cause of death and risk of death for people living with HIV admitted to hospital: A systematic review and meta-analysis
Introduction Despite increasing access to HIV treatment and care, HIV-associated deaths remain high. We aimed to summarize global and regional trends in risk and causes of death among people living...
Relationship between onychomycosis and HIV: A systematic review
Background/Objectives: Onychomycosis is a fungal nail infection that may present with severe, atypical, or treatment-resistant features in people living with HIV. Despite its clinical importance, evidence regarding its epidemiology, causative...
Mpox coinfections and clinical manifestation in Africa: A systematic review and meta-analysis
BACKGROUND: Mpox remains a significant public health challenge in Africa, where endemic transmission persists alongside a high burden of other infectious diseases. Although the epidemiology and clinical impact of coinfections...
Mpox clinical outcomes in people with and without HIV treated with tecovirimat: A systematic review
Mpox poses heightened risks for immunocompromised individuals, particularly people with HIV (PWH), yet evidence on clinical outcomes and antiviral treatment remains limited. We conducted a systematic review in accordance with...
