Category Archives: Co-infections

HIV, tuberculosis, and food insecurity in Africa—A syndemics-based scoping review

2022

The double burden of HIV/AIDS and tuberculosis (TB), coupled with endemic and problematic food insecurity in Africa, can interact to negatively impact health outcomes, creating a syndemic. For people living...

Prevalence of Hepatitis B and C among HIV infected patients in Nepal over 1990–2020

2021

Background Hepatitis B and C (HBV and HCV) are viral infections caused by corresponding viruses. Here in this study we planned to conduct this meta-analysis to pool data on the...

Intersectoral costs of sexually transmitted infections (STIs) and HIV: A systematic review of cost-of-illness (COI) studies

2021

BACKGROUND: Sexually transmitted infections (STIs) and HIV can generate costs both within and outside the health sector (i.e. intersectoral costs). This systematic review aims (i) to explore the intersectoral costs...

A systematic review and meta-analysis of inpatient mortality associated With nosocomial and community COVID-19 exposes the vulnerability of immunosuppressed adults

2021

BACKGROUND: Little is known about the mortality of hospital-acquired (nosocomial) COVID-19 infection globally. We investigated the risk of mortality and critical care admission in hospitalised adults with nosocomial COVID-19, relative...

Safety of tenofovir disoproxil fumarate for pregnant women facing the coronavirus disease 2019 pandemic

2021

We assessed the teratogenicity of tenofovir, a human immunodeficiency virus (HIV) drug similar to remdesivir that is currently being evaluated for the treatment of coronavirus disease 2019 (COVID-19). Using US...

The likelihood of severe COVID-19 outcomes among PLHIV with various comorbidities: A comparative frequentist and Bayesian meta-analysis approach

2021

INTRODUCTION: The SARS-CoV-2 virus can currently pose a serious health threat and can lead to severe COVID-19 outcomes, especially for populations suffering from comorbidities. Currently, the data available on the...

Impact of chronic HIV infection on SARS-CoV-2 infection, COVID-19 disease and vaccines

2021

PURPOSE OF REVIEW: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has developed into a global pandemic that affect the health of hundreds of millions worldwide. In particular, SARS-CoV-2 infection...

Social and behavioral impacts of COVID-19 on people living with HIV: Review of the first year of research

2021

PURPOSE OF THE REVIEW: The SARS-CoV-2 (COVID-19) pandemic brought unprecedented social change with the most severe impacts on the most vulnerable populations, including people living with HIV (PLWH). This review...

Tuberculosis screening among ambulatory people living with HIV: A systematic review and individual participant data meta-analysis

2021

Background The WHO-recommended tuberculosis screening and diagnostic algorithm in ambulatory people living with HIV is a four-symptom screen (known as the WHO-recommended four symptom screen [W4SS]) followed by a WHO-recommended...

Barriers to and enablers of uptake of antiretroviral therapy in integrated HIV and tuberculosis treatment programmes in sub-Saharan Africa: A systematic review and meta-analysis

2021

Introduction Programmes that merge management of Human Immunodeficiency Virus (HIV) and tuberculosis (TB) aim to improve HIV/TB co-infected patients’ access to comprehensive treatment. However, several reports from sub-Saharan Africa (SSA)...

HIV and SARS-CoV-2 co-infection: Epidemiological, clinical features, and future implications for clinical care and public health for people living with HIV (PLWH) and HIV most-at-risk groups

2021

Purpose of Review The purpose of this review is using the currently available clinical and epidemiological data, to identify key aspects to improve both the clinical management and public health...

Association between rectal gonorrhoea and HIV incidence in men who have sex with men: A meta-analysis

2021

Background: Incidence of rectal gonorrhoea (GC) has been hypothesised as a correlate of HIV exposure in prevention trials of men who have sex with men (MSM). High rectal GC incidence in...

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