Category Archives: Co-infections
Impact of diagnostic strategies for tuberculosis using lateral flow urine lipoarabinomannan assay in people living with HIV
Background: Tuberculosis is the primary cause of hospital admission in people living with HIV, and the likelihood of death in the hospital is unacceptably high. The Alere Determine TB LAM Ag...
Same-day antiretroviral therapy initiation for people living with HIV who have tuberculosis symptoms: A systematic review
Objectives Tuberculosis symptoms are very common among people living with HIV (PLHIV) initiating antiretroviral therapy (ART), are not specific for tuberculosis disease and may result in delayed ART start. The...
Economic and modeling evidence for tuberculosis preventive therapy among people living with HIV: A systematic review and meta-analysis
BACKGROUND: Human immunodeficiency virus (HIV) is the strongest known risk factor for tuberculosis (TB) through its impairment of T-cell immunity. Tuberculosis preventive treatment (TPT) is recommended for people living with...
Tuberculosis preventive therapy for people living with HIV: A systematic review and network meta-analysis
BACKGROUND: Tuberculosis (TB) preventive therapy (TPT) is an essential component of care for people living with HIV (PLHIV). We compared efficacy, safety, completion, and drug-resistant TB risk for currently recommended...
The latent tuberculosis cascade-of-care among people living with HIV: A systematic review and meta-analysis
BACKGROUND: Tuberculosis preventive therapy (TPT) reduces TB-related morbidity and mortality in people living with HIV (PLHIV). Cascade-of-care analyses help identify gaps and barriers in care and develop targeted solutions. A...
The catastrophic HPV/HIV dual viral oncogenomics in concert with dysregulated alternative splicing in cervical cancer
Cervical cancer is a public health problem and has devastating effects in low-to-middle-income countries (LTMICs) such as the sub-Saharan African (SSA) countries. Infection by the human papillomavirus (HPV) is the...
High-risk human papillomavirus infection among women living with HIV in Latin America and the Caribbean: A systematic review and meta-analysis
We carried out a systematic review to summarize available data regarding prevalence of high-risk human papillomavirus (HR-HPV) among women living with HIV (WLHIV) in Latin America and the Caribbean (LAC)....
Genetic factors associated with tuberculosis-related clinical outcomes in HIV-infected Black African patients: A systematic review and meta-analysis
Aim: To evaluate the genetic factors influencing tuberculosis (TB) clinical outcomes in HIV-infected Black African patients. Materials & methods: We systematically searched and identified eligible publications from >550 databases indexed...
Strategies for the diagnosis and management of meningitis in HIV-infected adults in resource limited settings
INTRODUCTION: The incidence of human immunodeficiency virus-1 (HIV-1) associated meningitis has been declining in the post-combination antiretroviral treatment (ART) era, although survival rates remain low for the common causes like...
Seroprevalence estimates of latent and acute toxoplasma infections in HIV(+) people-call for action in underprivileged communities
We undertook a comprehensive, systematic review of observational studies to estimate respective seroprevalences of latent and acute Toxoplasma gondii infections in HIV(+) people at the global, regional and country levels;...
Clinical progression of COVID-19 coinfection in people living with the human immunodeficiency virus: Scoping review
OBJECTIVES: to map the production of scientific knowledge on the clinical progression of COVID-19 coinfection in people living with the human immunodeficiency virus (HIV). METHODS: scoping review, with search strategies...
