Category Archives: Co-infections
Global, regional, and national estimates of hepatitis C virus (HCV) infection incidence among people who inject drugs and number of new annual HCV infections attributable to injecting drug use: A multi-stage analysis
Background: Measuring progress towards the WHO 2030 target for hepatitis C virus (HCV) elimination among people who inject drugs (PWID)-an incidence of two or fewer infections per 100 person-years-has been challenging...
Experiences of older people living with human immunodeficiency virus comorbidity attending coordinated healthcare services
BACKGROUND: Older people living with human immunodeficiency virus (OPLWHIV) on antiretroviral therapy are aging and face an increased risk of non-communicable diseases. The burden is costly and demands sustainable care...
Insights into gastrointestinal manifestation of human immunodeficiency virus: A narrative review
Human immunodeficiency virus (HIV) modifies CD4-positive cells, resulting in immunodeficiency and a wide range of gastrointestinal (GI) manifestations. The burden of HIV-related GI illnesses has significantly evolved with the widespread...
Gastrointestinal Escherichia coli in men who have sex with men: A systematic review
OBJECTIVE: This systematic review aimed to explore any demographic, biological and behavioural characteristics of men who have sex with men (MSM) with diarrhoeagenic E.coli. DESIGN/METHODS: We searched MEDLINE, EMBASE, and...
Prevalence of HHV-6 detection among people living with HIV: A systematic review and meta-analysis
Human herpesvirus 6 (HHV-6) is a ubiquitous virus with significant implications for immunocompromised individuals, particularly people living with HIV (PLWH). This study aimed to estimate the prevalence of HHV-6 detection...
Impacts of the COVID-19 pandemic on the HIV care continuum and associated factors in high-income nations: A mixed-methods systematic review
The COVID-19 pandemic has significantly impacted the HIV care continuum (HCC), presenting challenges while also driving positive transformations globally. This study examines the impact of the COVID-19 pandemic on HCC...
Invasive Neisseria meningitidis subtype C in gay, bisexual and other men who have sex with men: A systematic review
INTRODUCTION: Outbreaks of invasive Neisseria meningitidis subtype C in networks of gay, bisexual and other men who have sex with men (MSM) have been reported. We aimed to explore any...
Preventing unintended pregnancies and HIV through self-care interventions in east and southern Africa: Findings from a structured review
OBJECTIVE: To identify promising interventions targeting young people in East and Southern Africa through self-care practices, with a focus on prevention of unintended pregnancies and HIV and develop four evidence-based...
Acceptability of self-sampling and self-testing for infections: A rapid systematic review on public users’ views
Background Self-sampling and self-testing have been increasingly used for sexually transmitted infections (STIs) and quickly became widespread during the COVID-19 pandemic. User acceptability, preferences, and experiences are important factors affecting...
The efficacy of Cotrimoxazole for the prevention of Pneumocystis jirovecii pneumonia among HIV-exposed and infected children: A systematic review
BACKGROUND: HIV-related opportunistic infections like Pneumocystis jirovecii Pneumonia (PCP) remain a major contributor to child morbidity and mortality globally. PCP accounts for over 60% of AIDS in the first year...
Economic evaluations of sexual and reproductive health (SRH) services in low- and middle-income countries (LMICs): A systematic review
BACKGROUND: Sexual and reproductive health (SRH) programmes and services aim to prevent complications of pregnancy and childbirth, unintended pregnancies, unsafe abortions, complications caused by sexually transmitted infections, including HIV, sexual...
