Category Archives: Co-infections
Are Candida albicans isolates from the oral cavity of HIV-infected patients more virulent than from non-HIV-infected patients? Systematic review and meta-analysis
Candida albicans is the main causative agent of oral lesions in HIV-infected patients and its oral colonization is a potential source of systemic dissemination. Although the high prevalence of lesions...
Implications of COVID-19 in high burden countries for HIV/TB: A systematic review of evidence
BACKGROUND: The triple burden of COVID-19, tuberculosis and human immunodeficiency virus is one of the major global health challenges of the twenty-first century. In high burden HIV/TB countries, the spread...
Hepatitis E seroprevalence and viremia rate in immunocompromised patients: A systematic review and meta-analysis
BACKGROUND AND AIMS: Hepatitis E is an infectious disease of the liver caused by the hepatitis E virus (HEV). Immunocompromised patients present a particular risk group, as chronification of hepatitis...
The prevalence of latent and acute toxoplasmosis in HIV-infected pregnant women: A systematic review and meta-analysis
OBJECTIVE: HIV in pregnancy is not only important for mother-to-child HIV transmission, but also it assumes additional importance because HIV increases susceptibility to opportunistic infections, leading to increased morbidity and...
Review of sexualized drug use associated with sexually transmitted and blood-borne infections in gay, bisexual and other men who have sex with men
PURPOSE: The aim of the present study was to quantify associations between sexualized drug use (SDU) and sexually-transmitted and blood-borne infection (STBBI) diagnoses in gay, bisexual and other men who...
Diagnostic accuracy of serum (1,3)-beta-D-glucan for Pneumocystis jirovecii pneumonia: A systematic review and meta-analysis
Serum 1,3-β-d-glucan (BG) assay may be helpful as a marker for the diagnosis of Pneumocystis jiroveci pneumonia (PJP) and invasive fungal infection (IFI). We conducted a systematic review to assess the diagnostic...
Prevalence and type distribution of human papillomavirus recovered from the uterine cervix of Nigerian women: A systematic review and meta-analysis
BACKGROUND: Infection with an oncogenic type of human papillomavirus is a prerequisite for the development of precancerous cervical lesions and its subsequent progression to cervical cancer. With an alarming increase...
Direct-acting antivirals for HCV treatment in older patients: A systematic review and meta-analysis
The advent of highly effective and well-tolerated direct antiviral antivirals (DAAs) has dramatically changed the landscape of chronic hepatitis C. The effect of DAAs in older adults is difficult to...
Clostridium difficile in immunocompromised hosts: A review of epidemiology, risk factors, treatment, and prevention
Clostridium difficile is a significant pathogen in healthcare today, impacting both hospitalized and community-based patients. Immunocompromised patients experience a high incidence of C. difficile infection, ranging from 6% to 33%...
Burden of Talaromyces marneffei infection in people living with HIV/AIDS in Asia during ART era: A systematic review and meta-analysis
BACKGROUND: Talaromyces marneffei (TM) is a dimorphic fungus mainly prevalent in Southeast Asian countries, which often causes disseminated life-threatening infection. TM infection often occurs in HIV/AIDS patients even in the...
A systematic review and meta-analysis to assess the association between urogenital schistosomiasis and HIV/AIDS infection
BACKGROUND: Urogenital schistosomiasis and HIV/AIDS infections are widespread in sub-Saharan Africa (SSA) leading to substantial morbidity and mortality. The co-occurrence of both diseases has led to the possible hypothesis that...
