Category Archives: Co-infections
Effectiveness of pneumococcal conjugate vaccination against invasive pneumococcal disease among children with and those without HIV infection: A systematic review and meta-analysis
BACKGROUND: HIV-infected children are at a higher risk of Invasive Pneumococcal Disease (IPD) and its mortality, even in the era of antiretroviral therapy. Therefore, an effective vaccination strategy would be...
Global population-level association between herpes simplex virus 2 prevalence and HIV prevalence
BACKGROUND: Our objective was to assess the population-level association between herpes simplex virus 2 (HSV-2) and HIV prevalence. METHODS: Reports of HSV-2 and HIV prevalence were systematically reviewed and synthesized...
Sociodemographic and health profile of TB/HIV co-infection in Brazil: A systematic review
OBJECTIVE: to ascertain the epidemiological profile of TB/HIV co-infection in Brazilian scenarios. METHOD: this is a systematic review conducted via electronic search in databases PubMed, EMBASE, LILACS and SciELO, having...
Using the barriers and facilitators to linkage to HIV care to inform hepatitis C virus (HCV) linkage to care strategies for people released from prison: Findings from a systematic review
Elimination of hepatitis C virus (HCV) among short-term sentenced prison populations will require improved access to HCV care and specific strategies dedicated to linkage upon release. Prison-based HCV care has...
Epidemiology of Chlamydia trachomatis in the Middle East and North Africa: A systematic review, meta-analysis, and meta-regression
BACKGROUND: The epidemiology of Chlamydia trachomatis in the Middle East and north Africa is poorly understood. We aimed to provide a comprehensive epidemiological assessment of C trachomatis infection in the...
Treatment outcomes and antiretroviral uptake in multidrug-resistant tuberculosis and HIV co-infected patients in sub Saharan Africa: A systematic review and meta-analysis
BACKGROUND: Multidrug-resistant tuberculosis (MDR-TB) in HIV endemic settings is a major threat to public health. MDR-TB is a substantial and underreported problem in Sub-Saharan Africa (SSA), with recognised cases projected...
Immunological efficacy of Tenofovir disproxil fumarate-containing regimens in Patients With HIV-HBV coinfection: A systematic review and meta-analysis
Background: Hepatitis B virus (HBV) coinfection is common in HIV-positive patients. HIV infection modifies the natural course of HBV infection, leading to a faster progression of liver-related morbidity and mortality...
Histoplasmosis and tuberculosis co-occurrence in people with advanced HIV
Distinguishing between histoplasmosis, tuberculosis (TB), and co-occurrence of disease is a frequent dilemma for clinical staff treating people with advanced Human Immunodeficiency Virus (HIV) infection. This problem is most frequently...
Sexually transmitted hepatitis C virus infections: Current trends, and recent advances in understanding the spread in men who have sex with men
INTRODUCTION: Hepatitis C virus (HCV) is a major public health threat. Although the recent availability of highly effective directly acting antivirals created optimism towards HCV elimination, there is ongoing transmission...
HIV prevalence among tuberculosis patients in sub-Saharan Africa: A systematic review and meta-analysis
HIV associated tuberculosis (TB) morbidity and mortality is a major concern in sub-Saharan Africa. Understanding the level of HIV infection among TB patients is vital for adequate response. We conducted...
High HIV and active tuberculosis prevalence and increased mortality risk in adults with symptoms of TB: A systematic review and meta-analyses
INTRODUCTION: HIV and tuberculosis (TB) remain leading causes of preventable death in low- and middle-income countries (LMICs). The World Health Organization (WHO) recommends HIV testing for all individuals with TB...
