Category Archives: Co-infections

Global, regional, and national estimates of hepatitis C virus (HCV) infection incidence among people who inject drugs and number of new annual HCV infections attributable to injecting drug use: A multi-stage analysis

2025

Background: Measuring progress towards the WHO 2030 target for hepatitis C virus (HCV) elimination among people who inject drugs (PWID)-an incidence of two or fewer infections per 100 person-years-has been challenging...

Experiences of older people living with human immunodeficiency virus comorbidity attending coordinated healthcare services

2025

BACKGROUND: Older people living with human immunodeficiency virus (OPLWHIV) on antiretroviral therapy are aging and face an increased risk of non-communicable diseases. The burden is costly and demands sustainable care...

Insights into gastrointestinal manifestation of human immunodeficiency virus: A narrative review

2025

Human immunodeficiency virus (HIV) modifies CD4-positive cells, resulting in immunodeficiency and a wide range of gastrointestinal (GI) manifestations. The burden of HIV-related GI illnesses has significantly evolved with the widespread...

Impacts of the COVID-19 pandemic on the HIV care continuum and associated factors in high-income nations: A mixed-methods systematic review

2025

The COVID-19 pandemic has significantly impacted the HIV care continuum (HCC), presenting challenges while also driving positive transformations globally. This study examines the impact of the COVID-19 pandemic on HCC...

Invasive Neisseria meningitidis subtype C in gay, bisexual and other men who have sex with men: A systematic review

2024

INTRODUCTION: Outbreaks of invasive Neisseria meningitidis subtype C in networks of gay, bisexual and other men who have sex with men (MSM) have been reported. We aimed to explore any...

The efficacy of Cotrimoxazole for the prevention of Pneumocystis jirovecii pneumonia among HIV-exposed and infected children: A systematic review

2025

BACKGROUND: HIV-related opportunistic infections like Pneumocystis jirovecii Pneumonia (PCP) remain a major contributor to child morbidity and mortality globally. PCP accounts for over 60% of AIDS in the first year...

Economic evaluations of sexual and reproductive health (SRH) services in low- and middle-income countries (LMICs): A systematic review

2025

BACKGROUND: Sexual and reproductive health (SRH) programmes and services aim to prevent complications of pregnancy and childbirth, unintended pregnancies, unsafe abortions, complications caused by sexually transmitted infections, including HIV, sexual...

The global prevalence and impact of steatotic liver disease and viral infections: A systematic review and meta-analysis

2025

Background: Steatotic liver disease (SLD) affects ~30% of adults worldwide. The global population is continuously threatened by epidemic and endemic viral diseases. This study aims to thoroughly examine the interaction...

Comprehensive appraisal of the association between sexually transmitted infections and prostate cancer: A scoping review of empirical studies, reviews, and meta-analyses

2025

We performed a scoping review on the association of sexually transmitted infections (STIs) with prostate cancer and identified knowledge gaps. Searching four databases (Medline, Embase, Scopus, and Cochrane) identified 286...

Impact of HIV infection on hepatocellular carcinoma: A long-term prognostic analysis

2025

Purpose: This study aims to explore the influence of human immunodeficiency virus (HIV) infection on the prognosis of patients with hepatocellular carcinoma (HCC). Methods: According to the search strategy, we...

Prevalence and burden of HBV-HIV co-morbidity: A global systematic review and meta-analysis

2025

Introduction Hepatitis B is a serious liver infection caused by the hepatitis B virus (HBV). Because of the shared modes of transmission, co-infections of HBV are common among people living...

Preventing unintended pregnancies and HIV through self-care interventions in east and southern Africa: Findings from a structured review

2025

OBJECTIVE: To identify promising interventions targeting young people in East and Southern Africa through self-care practices, with a focus on prevention of unintended pregnancies and HIV and develop four evidence-based...

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