Category Archives: Co-infections

Interferon-free therapies for patients with chronic hepatitis C genotype 3 infection: A systematic review

2016

Treatment of hepatitis C virus (HCV) infection with genotype 3 remains a challenge. The HCV elimination rate with direct-acting antivirals (DAAs) is lower than the values reported for other HCV...

Association between diabetes mellitus and active tuberculosis in Africa and the effect of HIV

2017

OBJECTIVE: To determine current evidence for the association between diabetes and active tuberculosis in Africa, and how HIV modifies, or not, any association between diabetes and active tuberculosis. METHODS: We...

Alcohol use disorder and its impact on chronic hepatitis C virus and human immunodeficiency virus infections

2016

Alcohol use disorder (AUD) and hepatitis C virus (HCV) infection frequently co-occur. AUD is associated with greater exposure to HCV infection, increased HCV infection persistence, and more extensive liver damage...

Effect of secondary preventive therapy on recurrence of tuberculosis in HIV-infected individuals: A systematic review

2017

Human immunodeficiency virus (HIV)-infected individuals successfully treated for tuberculosis (TB) remain at risk of recurrence of the disease, especially in high TB incidence settings. We performed a systematic review, investigating...

Seroprevalence of hepatitis C virus among people living with HIV/AIDS in Latin America and the Caribbean: A systematic review

2016

BACKGROUND: Studies have shown that the immunosuppression induced by the human immunodeficiency virus (HIV) accelerates the natural history of liver disease associated with hepatitis C virus (HCV), with 3- to...

Prisoners co-infected with tuberculosis and HIV: A systematic review

2016

INTRODUCTION: Almost from the beginning of the HIV epidemic in 1981, an association with tuberculosis (TB) was recognized. This association between HIV and TB co-infection has been particularly evident amongst...

Hepatitis C virus coinfection as a risk factor for osteoporosis and fracture

2016

PURPOSE OF REVIEW: With increased survival of HIV-infected patients, osteoporotic fractures have developed as a major cause of morbidity in these patients, and chronic hepatitis C virus (HCV) coinfection has...

Association of HIV infection with extrapulmonary tuberculosis: A systematic review

2017

PURPOSE: HIV/AIDS is a known risk factor for the development of pulmonary tuberculosis (PTB). However, the association is less clear between HIV and extrapulmonary tuberculosis (EPTB). We conducted a systematic...

Risk of late relapse or reinfection with hepatitis C virus after achieving a sustained virological response: A systematic review and meta-analysis

2016

BACKGROUND: Treatment for hepatitis C virus (HCV) can lead to sustained virological response (SVR) in over 90% of people. Subsequent recurrence of HCV, either from late relapse or reinfection, reverses...

Hepatitis C virus seroprevalence in adults in Africa: A systematic review and meta-analysis

2016

With the introduction of more efficient treatments for hepatitis C virus (HCV), improved epidemiological information is required at the country level to allow evidence-based policymaking for elaboration of national strategies...

Toxoplasmic encephalitis relapse rates with pyrimethamine-based therapy: Systematic review and meta-analysis

2017

Toxoplasmic encephalitis (TE) is caused by Toxoplasma gondii infection and can be a life-threatening disease in immunocompromised patients. This study evaluated the rate of relapse associated with pyrimethamine-based maintenance therapy...

Use of transient elastography in patients with HIV-HCV coinfection: A systematic review and meta-analysis

2016

BACKGROUND AND AIM: Patients with HIV-hepatitis C virus (HCV) coinfection progress towards liver fibrosis and cirrhosis more rapidly compared with HCV mono-infected individuals. This necessitates an accurate assessment of liver...

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