Category Archives: Co-infections

The risks for HIV and sexually transmitted infections among men who have sex with men who engage in chemsex in low- and middle-income countries: A mixed methods systematic reviewa and meta-analysis

2024

Chemsex, the use of drugs during and/or prior to sex, has been found to increase the risk of HIV and sexually transmitted infections (STI) among men who have sex with...

Prevalence of oropharyngeal candidiasis and distribution of Candida species among people living with human immunodeficiency virus in Africa: A systematic review and meta-analysis

2024

BACKGROUND: The incidence of oropharyngeal candidiasis among people living with human immunodeficiency virus in Africa is on the rise. Oropharyngeal candidiasis is mainly caused by C.albicans; however, a shift in...

The impact of immunosuppression on the mortality and hospitalization of Monkeypox: A systematic review and meta-analysis of the 2022 outbreak

2024

Background: Limited data is available regarding the severity and mortality of Mpox in individuals with immunocompromised conditions. Therefore, we performed this meta-analysis to understand the impact of HIV- or non-HIV-associated immunosuppression...

Non-mycobacteria tuberculosis in Africa: A literature review

2023

BACKGROUND: Non-tuberculous mycobacteria (NTM) have been reported to cause pulmonary and extrapulmonary infections. These NTMs are often misdiagnosed as MTB due to their similar clinical presentations to tuberculosis, leading to...

Incidence rate of tuberculosis among HIV infected children in Ethiopia: Systematic review and meta-analysis

2024

Background Tuberculosis is one the leading causes of death from a single infectious disease, caused by the bacillus mycobacterium tuberculosis. In Ethiopia, even though several primary studies have been conducted...

A systematic review of barriers and facilitators to antenatal screening for HIV, syphilis or hepatitis B in Asia: Perspectives of pregnant women, their relatives and health care providers

2024

BACKGROUND: Despite improvements, the prevalence of HIV, syphilis, and hepatitis B remains high in Asia. These sexually transmitted infections (STIs) can be transmitted from infected mothers to their children. Antenatal...

Interventions aimed at increasing syphilis screening among non-pregnant individuals in healthcare settings: A systematic review and meta-analysis

2024

Syphilis remains a pressing public health concern with potential severe morbidity if left untreated. To improve syphilis screening, targeted interventions are crucial, especially in at-risk populations. This systematic review synthesises...

COVID-19 vaccine acceptance and hesitancy among people living with HIV: Review and meta-analysis

2024

This study aims to estimate the COVID-19 vaccine acceptance and hesitancy among people living with HIV (PLWHA). A search for observational studies was conducted in five databases and preprinted literature....

Sexually transmitted infections, sexual life and risk behaviours of people living with schizophrenia: Systematic review and meta-analysis

2024

BACKGROUND: Sexually transmitted infections (STIs), along with sexual health and behaviour, have received little attention in schizophrenia patients. AIMS: To systematically review and meta-analytically characterise the prevalence of STIs and...

Aetiology of vaginal discharge, urethral discharge, and genital ulcer in sub-Saharan Africa: A systematic review and meta-regression

2024

BACKGROUND: Syndromic management is widely used to treat symptomatic sexually transmitted infections in settings without aetiologic diagnostics. However, underlying aetiologies and consequent treatment suitability are uncertain without regular assessment. This...

Reactivation of Trypanosoma cruzi infection in immunosuppressed patients: A systematic review and meta-analysis

2024

Background: The risk of Trypanosoma cruzi reactivation is poorly understood. Previous studies evaluating the risk of reactivation report imprecise findings, and recommendations for monitoring and management from clinical guidelines rely...

Systematic review and meta-analysis of the global prevalence of sexually transmitted infections in people living with HIV and associated risk factors

2023

People living with HIV (PLWH) constitute a vulnerable population for acquiring additional sexually transmitted infections (STIs). This study was conducted to provide a summary of the evidence on the global...

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