Category Archives: Co-infections
The effect of tuberculosis treatment on virologic and CD4+ cell count response to combination antiretroviral therapy: A systematic review
OBJECTIVES: To determine the impact of tuberculosis (TB) treatment at the time of combination antiretroviral therapy (cART) initiation on virologic and CD4 cell count response to cART. METHODS:: Systematic review...
A systematic review of the effects of visual inspection with acetic acid, cryotherapy, and loop electrosurgical excision procedures for cervical dysplasia in HIV-infected women in low- and middle-income countries
BACKGROUND: Cervical cancer, almost all of which is caused by human papillomavirus, accounts for 12% of female cancers worldwide and is more common among HIV-infected women. Nine of 10 deaths...
Incidence of sexually transmitted hepatitis C virus infection in HIV-positive men who have sex with men: A systematic review and meta-analysis
OBJECTIVE: The epidemiology of the incidence of sexually transmitted hepatitis C virus (HCV) infection in HIV-positive men who have sex with men (MSM) is only partially understood. In the presence...
Early versus delayed antiretroviral therapy for HIV and Tuberculosis co-infected patients: A systematic review and meta-analysis of randomized controlled trials
OBJECTIVE: To compare important clinical outcomes between early and delayed initiation of antiretroviral therapy (ART) in adults who had a co-infection of human immunodeficiency virus (HIV) and tuberculosis (TB). METHODS:...
The impact of water, sanitation, and hygiene interventions on the health and well-being of people living with HIV: A systematic review
BACKGROUND: Access to improved water supply and sanitation is poor in low-income and middle-income countries. Persons living with HIV/AIDS (PLHIV) experience more severe diarrhea, hospitalizations, and deaths from diarrhea because...
Using hepatitis C prevalence to estimate HIV epidemic potential among people who inject drugs in the Middle East and North Africa
OBJECTIVES: The objective of this study is to understand the association between HIV and hepatitis C virus (HCV) among people who inject drugs (PWIDs) in the Middle East and North...
Osteoporosis and fractures in HIV/hepatitis C virus coinfection: A systematic review and meta-analysis
OBJECTIVE: There is growing evidence that fracture risk is increased in individuals with HIV and/or hepatitis C virus (HCV) infection. We systematically reviewed the literature to determine whether prevalence of...
Prevalence of tuberculosis in post-mortem studies of HIV-infected adults and children in resource-limited settings: A systematic review and meta-analysis
OBJECTIVES: Tuberculosis (TB) is estimated to be the leading cause of HIV-related deaths globally. However, since HIV-associated TB frequently remains unascertained, we systematically reviewed autopsy studies to determine the true...
Discontinuing pneumocystis jirovecii pneumonia prophylaxis in HIV-infected patients with a CD4 cell count <200 cells/mm3
OBJECTIVE: To review the evidence for discontinuing primary and secondary Pneumocystis jirovecii pneumonia (PJP) prophylaxis in HIV-infected patients with a CD4 count <200 cells/mm3. DATA SOURCES: We conducted a literature...
Hepatitis C virus increases the risk of kidney disease among HIV-positive patients: Systematic review and meta-analysis
BACKGROUND: Kidney disease has become an important co-morbidity among human immunodeficiency virus-infected patients as they live longer in the era of highly effective antiretroviral therapy. It remains unclear how co-infection...
The effect of HIV-hepatitis C co-infection on bone mineral density and fracture: A meta-analysis
OBJECTIVE: There is a variable body of evidence on adverse bone outcomes in HIV patients co-infected with hepatitis C virus (HCV). We examined the association of HIV/HCV co-infection on osteoporosis...
The effect of early initiation of antiretroviral therapy in TB/HIV coinfected patients: A systematic review and meta-analysis
BACKGROUND: The importance of early initiation of antiretroviral therapy (ART) for tuberculosis (TB) and HIV coinfected patients is controversial. We conducted a systematic review and meta-analysis to assess the effect...
